Nicotinamide Riboside Augments Human Macrophage Migration via SIRT3-Mediated Prostaglandin E2 Signaling

Nicotinamide Riboside Augments Human Macrophage Migration via SIRT3-Mediated Prostaglandin E2 Signaling

NAD<sup>+</sup> boosting via nicotinamide riboside (NR) confers anti-inflammatory effects. However, its underlying mechanisms and therapeutic potential remain incompletely defined. Here, we showed that NR increased the expression of CC-chemokine receptor 7 (CCR7) in human M1 macrophages...

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Bibliographic Details
Main Authors: Jing Wu, Maximilian Bley, Russell S. Steans, Allison M. Meadows, Rebecca D. Huffstutler, Rong Tian, Julian L. Griffin, Michael N. Sack
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
chemotaxis
macrophage migration
NAD<sup>+</sup> boosting
nicotinamide riboside
prostaglandin E2
SIRT3
Online Access:https://www.mdpi.com/2073-4409/13/5/455

Internet

https://www.mdpi.com/2073-4409/13/5/455

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