Adaptive Multiple Testing Procedure for Clinical Trials with Urn Allocation
This work combines the Urn allocation and O’Brien and Fleming multiple testing procedure to compare two treatments in clinical trials in a novel way. It is shown that this approach overcomes the constraints that previously made it challenging to apply the original adaptive design to clinical trials....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-09-01
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| Series: | Mathematics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-7390/11/18/3965 |