Adaptive Multiple Testing Procedure for Clinical Trials with Urn Allocation

Adaptive Multiple Testing Procedure for Clinical Trials with Urn Allocation

This work combines the Urn allocation and O’Brien and Fleming multiple testing procedure to compare two treatments in clinical trials in a novel way. It is shown that this approach overcomes the constraints that previously made it challenging to apply the original adaptive design to clinical trials....

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Bibliographic Details
Main Authors:	Hanan Hammouri, Mohammed Ali, Marwan Alquran, Areen Alquran, Ruwa Abdel Muhsen, Belal Alomari
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	Mathematics
Subjects:	statistical algorithm sequential group test O’Brien and Fleming type I error and power simulations SAS software
Online Access:	https://www.mdpi.com/2227-7390/11/18/3965

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