T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections

T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections

Summary: CD4+ T cells are key components of the immune response during lung infections and can mediate protection against tuberculosis (TB) or influenza. However, CD4+ T cells can also promote lung pathology during these infections, making it unclear how these cells control such discrepant effects....

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Bibliographic Details
Main Authors: Igor Santiago-Carvalho, Gislane Almeida-Santos, Bruna Gois Macedo, Caio Cesar Barbosa-Bomfim, Fabricio Moreira Almeida, Marcos Vinícios Pinheiro Cione, Trupti Vardam-Kaur, Mia Masuda, Sarah Van Dijk, Bruno Marcel Melo, Rogério Silva do Nascimento, Rebeka da Conceição Souza, Alba Lucínia Peixoto-Rangel, Robson Coutinho-Silva, Mario Hiroyuki Hirata, José Carlos Alves-Filho, José Maria Álvarez, Elena Lassounskaia, Henrique Borges da Silva, Maria Regina D’Império-Lima
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723014602

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