Dietary shochu kasu alleviates fatty liver induced by orotic acid
The effects of dietary shochu kasu (5%) on orotic acid-induced fatty liver were studied in rats. Liver triglyceride content of orotic acid-fed rats increased by 5-fold in comparison to basal group. Shochu kasu reduced triglyceride content by two-third. The activities of fatty acid synthase and pho...
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| Format: | Article |
| Language: | English |
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Bangladesh Pharmacological Society
2010-06-01
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| Series: | Bangladesh Journal of Pharmacology |
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| Online Access: | http://www.banglajol.info/index.php/BJP/article/view/5921/4749 |
| _version_ | 1819063529923149824 |
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| author | Yohanes Buang, Pius D. Ola, Teruyoshi Yanagita |
| author_facet | Yohanes Buang, Pius D. Ola, Teruyoshi Yanagita |
| author_sort | Yohanes Buang, Pius D. Ola, Teruyoshi Yanagita |
| collection | DOAJ |
| description | The effects of dietary shochu kasu (5%) on orotic acid-induced fatty liver were studied in rats. Liver triglyceride content of orotic acid-fed rats increased by 5-fold in comparison to basal group. Shochu kasu reduced triglyceride content by two-third. The activities of fatty acid synthase and phosphatidate phosphohydrolase significantly decreased that was approximately by 35% and 20%, respectively. The serum lipid levels however were nearly unchanged. The alleviation of fatty liver in rats with shochu kasu, therefore, was associated with the inhibition of fatty acid synthase and phosphatidate phosphohydrolase activities. |
| first_indexed | 2024-12-21T15:16:08Z |
| format | Article |
| id | doaj.art-fe5b3ecd98074f00b065102b26a2f8d5 |
| institution | Directory Open Access Journal |
| issn | 1991-007X 1991-0088 |
| language | English |
| last_indexed | 2024-12-21T15:16:08Z |
| publishDate | 2010-06-01 |
| publisher | Bangladesh Pharmacological Society |
| record_format | Article |
| series | Bangladesh Journal of Pharmacology |
| spelling | doaj.art-fe5b3ecd98074f00b065102b26a2f8d52022-12-21T18:59:09ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-007X1991-00882010-06-01515761Dietary shochu kasu alleviates fatty liver induced by orotic acidYohanes Buang, Pius D. Ola, Teruyoshi YanagitaThe effects of dietary shochu kasu (5%) on orotic acid-induced fatty liver were studied in rats. Liver triglyceride content of orotic acid-fed rats increased by 5-fold in comparison to basal group. Shochu kasu reduced triglyceride content by two-third. The activities of fatty acid synthase and phosphatidate phosphohydrolase significantly decreased that was approximately by 35% and 20%, respectively. The serum lipid levels however were nearly unchanged. The alleviation of fatty liver in rats with shochu kasu, therefore, was associated with the inhibition of fatty acid synthase and phosphatidate phosphohydrolase activities.http://www.banglajol.info/index.php/BJP/article/view/5921/4749Fatty liverOrotic acidTriacylglycerolShochu kasu |
| spellingShingle | Yohanes Buang, Pius D. Ola, Teruyoshi Yanagita Dietary shochu kasu alleviates fatty liver induced by orotic acid Bangladesh Journal of Pharmacology Fatty liver Orotic acid Triacylglycerol Shochu kasu |
| title | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_full | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_fullStr | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_full_unstemmed | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_short | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_sort | dietary shochu kasu alleviates fatty liver induced by orotic acid |
| topic | Fatty liver Orotic acid Triacylglycerol Shochu kasu |
| url | http://www.banglajol.info/index.php/BJP/article/view/5921/4749 |
| work_keys_str_mv | AT yohanesbuangpiusdolateruyoshiyanagita dietaryshochukasualleviatesfattyliverinducedbyoroticacid |