Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review
Abstract Purpose This scoping review aims to identify and describe knowledge gaps and research priorities in veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Methods An expert panel was recruited consisting of eight international experts from different backgrounds. First, a list of prior...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-11-01
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| Series: | Intensive Care Medicine Experimental |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40635-022-00478-z |
| _version_ | 1797986685603020800 |
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| author | Senta Jorinde Raasveld Carolien Volleman Alain Combes Lars Mikael Broman Fabio Silvio Taccone Elma Peters Sanne ten Berg Charissa E. van den Brom Holger Thiele Roberto Lorusso José P. S. Henriques Alexander P. J. Vlaar |
| author_facet | Senta Jorinde Raasveld Carolien Volleman Alain Combes Lars Mikael Broman Fabio Silvio Taccone Elma Peters Sanne ten Berg Charissa E. van den Brom Holger Thiele Roberto Lorusso José P. S. Henriques Alexander P. J. Vlaar |
| author_sort | Senta Jorinde Raasveld |
| collection | DOAJ |
| description | Abstract Purpose This scoping review aims to identify and describe knowledge gaps and research priorities in veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Methods An expert panel was recruited consisting of eight international experts from different backgrounds. First, a list of priority topics was made. Second, the panel developed structured questions using population, intervention, comparison and outcomes (PICO) format. All PICOs were scored and prioritized. For every selected PICO, a structured literature search was performed. Results After an initial list of 49 topics, eight were scored as high-priority. For most of these selected topics, current literature is limited to observational studies, mainly consisting of retrospective cohorts. Only for ECPR and anticoagulation, randomized controlled trials (RCTs) have been performed or are ongoing. Per topic, a summary of the literature is stated including recommendations for further research. Conclusions This scoping review identifies and presents an overview of knowledge gaps and research priorities in VA-ECMO. Current literature is mostly limited to observational studies, although with increasing attention for this patient population, more RCTs are finishing or ongoing. Translational research, from preclinical trials to high-quality or randomized controlled trials, is important to improve the standard practices in this critically ill patient population. Take-home message This scoping review identifies and presents an overview of research gaps and priorities in VA-ECMO. Translational research, from preclinical trials to high-quality or randomized controlled trials, is important to improve the standard practices in this critically ill patient population. |
| first_indexed | 2024-04-11T07:36:58Z |
| format | Article |
| id | doaj.art-fe5d2e1597cb4a9096cb3eee89597a83 |
| institution | Directory Open Access Journal |
| issn | 2197-425X |
| language | English |
| last_indexed | 2024-04-11T07:36:58Z |
| publishDate | 2022-11-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Intensive Care Medicine Experimental |
| spelling | doaj.art-fe5d2e1597cb4a9096cb3eee89597a832022-12-22T04:36:43ZengSpringerOpenIntensive Care Medicine Experimental2197-425X2022-11-0110111710.1186/s40635-022-00478-zKnowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping reviewSenta Jorinde Raasveld0Carolien Volleman1Alain Combes2Lars Mikael Broman3Fabio Silvio Taccone4Elma Peters5Sanne ten Berg6Charissa E. van den Brom7Holger Thiele8Roberto Lorusso9José P. S. Henriques10Alexander P. J. Vlaar11Department of Critical Care, Amsterdam University Medical Centers, Location Academic Medical CenterDepartment of Critical Care, Amsterdam University Medical Centers, Location Academic Medical CenterInstitute of Cardiometabolism and Nutrition, Sorbonne Université, INSERM, UMRS1166-ICANDepartment of Physiology and Pharmacology, Karolinska InstitutetDepartment of Intensive Care, Université Libre de Bruxelles, Hôpital Universitaire de Bruxelles (HUB)Heart Center, Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of AmsterdamHeart Center, Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of AmsterdamDepartment of Critical Care, Amsterdam University Medical Centers, Location Academic Medical CenterHeart Center Leipzig at University of Leipzig and Leipzig Heart Science GmbHDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Cardiovascular Research Institute Maastricht (CARIM)Heart Center, Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of AmsterdamDepartment of Critical Care, Amsterdam University Medical Centers, Location Academic Medical CenterAbstract Purpose This scoping review aims to identify and describe knowledge gaps and research priorities in veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Methods An expert panel was recruited consisting of eight international experts from different backgrounds. First, a list of priority topics was made. Second, the panel developed structured questions using population, intervention, comparison and outcomes (PICO) format. All PICOs were scored and prioritized. For every selected PICO, a structured literature search was performed. Results After an initial list of 49 topics, eight were scored as high-priority. For most of these selected topics, current literature is limited to observational studies, mainly consisting of retrospective cohorts. Only for ECPR and anticoagulation, randomized controlled trials (RCTs) have been performed or are ongoing. Per topic, a summary of the literature is stated including recommendations for further research. Conclusions This scoping review identifies and presents an overview of knowledge gaps and research priorities in VA-ECMO. Current literature is mostly limited to observational studies, although with increasing attention for this patient population, more RCTs are finishing or ongoing. Translational research, from preclinical trials to high-quality or randomized controlled trials, is important to improve the standard practices in this critically ill patient population. Take-home message This scoping review identifies and presents an overview of research gaps and priorities in VA-ECMO. Translational research, from preclinical trials to high-quality or randomized controlled trials, is important to improve the standard practices in this critically ill patient population.https://doi.org/10.1186/s40635-022-00478-zVeno-arterial extracorporeal membrane oxygenationExtracorporeal cardiopulmonary resuscitationResearch gaps |
| spellingShingle | Senta Jorinde Raasveld Carolien Volleman Alain Combes Lars Mikael Broman Fabio Silvio Taccone Elma Peters Sanne ten Berg Charissa E. van den Brom Holger Thiele Roberto Lorusso José P. S. Henriques Alexander P. J. Vlaar Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review Intensive Care Medicine Experimental Veno-arterial extracorporeal membrane oxygenation Extracorporeal cardiopulmonary resuscitation Research gaps |
| title | Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review |
| title_full | Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review |
| title_fullStr | Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review |
| title_full_unstemmed | Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review |
| title_short | Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review |
| title_sort | knowledge gaps and research priorities in adult veno arterial extracorporeal membrane oxygenation a scoping review |
| topic | Veno-arterial extracorporeal membrane oxygenation Extracorporeal cardiopulmonary resuscitation Research gaps |
| url | https://doi.org/10.1186/s40635-022-00478-z |
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