Cytotoxic Activity of Ursolic Acid Derivatives Obtained by Isolation and Oxidative Derivatization

Cytotoxic Activity of Ursolic Acid Derivatives Obtained by Isolation and Oxidative Derivatization

Structure-activity relationships of ursane-type pentacyclic triterpenes obtained from natural sources and by chemical derivatization are reviewed. Ursolic acid, corosolic acid, and a new ursane-type pentacyclic triterpene, 7,24-dihydroxyursolic acid, were isolated from the methanolic extract of the...

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Bibliographic Details
Main Authors:	Katsunori Tanaka, Koichi Fukase, Kishor Mazumder
Format:	Article
Language:	English
Published:	MDPI AG 2013-07-01
Series:	Molecules
Subjects:	ursolic acid Saurauja roxburghii cytotoxicity C6 rat glioma cell line A431 human skin carcinoma cell line dioxoruthenium(VI) tetraphenylporphyrin biomimetic oxidation cytochrome P450
Online Access:	http://www.mdpi.com/1420-3049/18/8/8929

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