Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, Turkey

Objective: The prevalence and incidence of multiple sclerosis may vary according to the influence of the altitude of a geographical area as well as the genetic and environmental factors. This study ained to determine the incidence and prevalence of multiple sclerosis in Edirne population.Material an...

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Main Authors: Yahya Çelik, Özlem Birgili, Aslı Kiyat, Baburhan Güldiken, Hülya Özkan, Hakan Yılmaz, Sebahattin Saip, Dilek Kuşçu, Nevin Sütlas, Jale Ağaoğlu, Ufuk Utku, Aksel Siva
Format: Article
Language:English
Published: Galenos Publishing House 2011-06-01
Series:Balkan Medical Journal
Subjects:
Online Access:http://balkanmedicaljournal.org/text.php3?id=754
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author Yahya Çelik
Özlem Birgili
Aslı Kiyat
Baburhan Güldiken
Hülya Özkan
Hakan Yılmaz
Sebahattin Saip
Dilek Kuşçu
Nevin Sütlas
Jale Ağaoğlu
Ufuk Utku
Aksel Siva
author_facet Yahya Çelik
Özlem Birgili
Aslı Kiyat
Baburhan Güldiken
Hülya Özkan
Hakan Yılmaz
Sebahattin Saip
Dilek Kuşçu
Nevin Sütlas
Jale Ağaoğlu
Ufuk Utku
Aksel Siva
author_sort Yahya Çelik
collection DOAJ
description Objective: The prevalence and incidence of multiple sclerosis may vary according to the influence of the altitude of a geographical area as well as the genetic and environmental factors. This study ained to determine the incidence and prevalence of multiple sclerosis in Edirne population.Material and Methods: Patients with a definite diagnosis of MS according to McDonald’s criteria, admitted to one of the three MS clinics in Edirne, were included in this two-stage study. Also the records of hospitals in İstanbul serving patients from Edirne, have been evaluated. Results: The prevalence rate of confirmed MS patients was 33.9/100000 (95% CI: 32-36) in 2003. The mean annual incidence was 3.48/100000 (95% CI: 2.90-4.00). Mean age of the patients was 36.5±9.6 years. Mean age at onset was 29.2±8.5 years. Mean duration of disease was 6.9±5.2 years. Overall, 69.2% had a relapsing-remitting course, 20.5% had a primary progressive course and 10.3% had a secondary progressive course. Mean Expanded Disability Status Scale score was 3.04±2.18. The prevalence and annual incidence after one year was 36.5 per 100000 (95% CI: 33.2-38.6) and 2.60 per 100000 (95% CI: 2.1-3.8), respectively.Conclusion: This is the first city-based MS prevalence study performed in Turkey. The MS prevalence in Edirne is similar to that of Greece and Bulgaria but lower than that of European countries.
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spelling doaj.art-fe689e0b96c84281ada8b1dc46c566ca2023-02-15T16:07:39ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312011-06-012802193196Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, TurkeyYahya ÇelikÖzlem BirgiliAslı KiyatBaburhan GüldikenHülya ÖzkanHakan YılmazSebahattin SaipDilek KuşçuNevin SütlasJale AğaoğluUfuk UtkuAksel SivaObjective: The prevalence and incidence of multiple sclerosis may vary according to the influence of the altitude of a geographical area as well as the genetic and environmental factors. This study ained to determine the incidence and prevalence of multiple sclerosis in Edirne population.Material and Methods: Patients with a definite diagnosis of MS according to McDonald’s criteria, admitted to one of the three MS clinics in Edirne, were included in this two-stage study. Also the records of hospitals in İstanbul serving patients from Edirne, have been evaluated. Results: The prevalence rate of confirmed MS patients was 33.9/100000 (95% CI: 32-36) in 2003. The mean annual incidence was 3.48/100000 (95% CI: 2.90-4.00). Mean age of the patients was 36.5±9.6 years. Mean age at onset was 29.2±8.5 years. Mean duration of disease was 6.9±5.2 years. Overall, 69.2% had a relapsing-remitting course, 20.5% had a primary progressive course and 10.3% had a secondary progressive course. Mean Expanded Disability Status Scale score was 3.04±2.18. The prevalence and annual incidence after one year was 36.5 per 100000 (95% CI: 33.2-38.6) and 2.60 per 100000 (95% CI: 2.1-3.8), respectively.Conclusion: This is the first city-based MS prevalence study performed in Turkey. The MS prevalence in Edirne is similar to that of Greece and Bulgaria but lower than that of European countries.http://balkanmedicaljournal.org/text.php3?id=754Multiple SclerosisprevalanceincidenceepidemiologyTurkey
spellingShingle Yahya Çelik
Özlem Birgili
Aslı Kiyat
Baburhan Güldiken
Hülya Özkan
Hakan Yılmaz
Sebahattin Saip
Dilek Kuşçu
Nevin Sütlas
Jale Ağaoğlu
Ufuk Utku
Aksel Siva
Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, Turkey
Balkan Medical Journal
Multiple Sclerosis
prevalance
incidence
epidemiology
Turkey
title Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, Turkey
title_full Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, Turkey
title_fullStr Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, Turkey
title_full_unstemmed Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, Turkey
title_short Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, Turkey
title_sort prevalence of multiple sclerosis in the metropolitan area of edirne city turkey
topic Multiple Sclerosis
prevalance
incidence
epidemiology
Turkey
url http://balkanmedicaljournal.org/text.php3?id=754
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