Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II), Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial evaluation
New polydentate hydrazone ligand, was synthesized by the condensation of 1,5-dimethyl-3-oxo-2-phenylpyrazole-4-carbaldehyde with adipodihydrazide. The structure of the synthesized ligand, Nâ²1,Nâ²6-bis((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl) methylene) adipohydrazide was elucidated...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2017-12-01
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| Series: | Beni-Suef University Journal of Basic and Applied Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2314853516302153 |
| _version_ | 1811218442513022976 |
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| author | Fathy A. El-Saied Mohamad M.E. Shakdofa Abdou S. El Tabl Mokhles M. Abd-Elzaher Nagy Morsy |
| author_facet | Fathy A. El-Saied Mohamad M.E. Shakdofa Abdou S. El Tabl Mokhles M. Abd-Elzaher Nagy Morsy |
| author_sort | Fathy A. El-Saied |
| collection | DOAJ |
| description | New polydentate hydrazone ligand, was synthesized by the condensation of 1,5-dimethyl-3-oxo-2-phenylpyrazole-4-carbaldehyde with adipodihydrazide. The structure of the synthesized ligand, Nâ²1,Nâ²6-bis((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl) methylene) adipohydrazide was elucidated by various analytical and spectroscopic techniques. The reactions of the ligand with zinc(II), copper(II), nickel(II), cobalt(II), manganese(II) and palladium(II) salts afforded homobinuclear metal complexes. Characterization and structure elucidation of the prepared complexes were achieved using different analytical and spectroscopic techniques. The analyses data indicated that this ligand behaved as N2O4 dibasic hexadentate ligand bonded covalency to the metal ions through the enolic carbonyl oxygen of hydrazide moiety and coordinated via carbonyl oxygen of antipyrine moiety and azomethine nitrogen atoms forming distorted octahedral geometry around the metal ions. The ESR spectra of copper(II) complexes (3) and (4) showed an axial symmetry with g||>gâ¥>ge, indicating distorted octahedral structure and presence of the unpaired electron in d(x2ây2) orbital. The microbicide studies of the ligand and its metal complexes (2), (3), (4), (5), (8), (11) and (13) showed that, all these complexes exhibit moderate to mild inhibitory effects on B. subtilis, E. coli while complexes (2), (3), (4) and (13) exhibit moderate to mild inhibitory effects on A. niger. Keywords: Hexadentate, Hydrazone, Antipyrine, ESR, Adipohydrazide, Microbicide |
| first_indexed | 2024-04-12T07:10:05Z |
| format | Article |
| id | doaj.art-fe6fe1d4f29e4709b93db59843471fcf |
| institution | Directory Open Access Journal |
| issn | 2314-8535 |
| language | English |
| last_indexed | 2024-04-12T07:10:05Z |
| publishDate | 2017-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Beni-Suef University Journal of Basic and Applied Sciences |
| spelling | doaj.art-fe6fe1d4f29e4709b93db59843471fcf2022-12-22T03:42:41ZengSpringerOpenBeni-Suef University Journal of Basic and Applied Sciences2314-85352017-12-0164310320Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II), Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial evaluationFathy A. El-Saied0Mohamad M.E. Shakdofa1Abdou S. El Tabl2Mokhles M. Abd-Elzaher3Nagy Morsy4Chemistry Department, Faculty of Science, El-Menoufia University, Shebin El-Kom, EgyptChemistry Department, Faculty of Sciences and Arts, Khulais, University of Jeddah, Saudi Arabia; Inorganic Chemistry Department, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt; Corresponding author at: Chemistry Department, Faculty of Sciences and Arts, Khulais, University of Jeddah, Saudi Arabia.Chemistry Department, Faculty of Science, El-Menoufia University, Shebin El-Kom, EgyptInorganic Chemistry Department, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, EgyptChemistry Department, Faculty of Sciences and Arts, Khulais, University of Jeddah, Saudi Arabia; Chemistry of Natural Compounds Department, National Research Centre, P.O. 12622, Dokki, Cairo, EgyptNew polydentate hydrazone ligand, was synthesized by the condensation of 1,5-dimethyl-3-oxo-2-phenylpyrazole-4-carbaldehyde with adipodihydrazide. The structure of the synthesized ligand, Nâ²1,Nâ²6-bis((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl) methylene) adipohydrazide was elucidated by various analytical and spectroscopic techniques. The reactions of the ligand with zinc(II), copper(II), nickel(II), cobalt(II), manganese(II) and palladium(II) salts afforded homobinuclear metal complexes. Characterization and structure elucidation of the prepared complexes were achieved using different analytical and spectroscopic techniques. The analyses data indicated that this ligand behaved as N2O4 dibasic hexadentate ligand bonded covalency to the metal ions through the enolic carbonyl oxygen of hydrazide moiety and coordinated via carbonyl oxygen of antipyrine moiety and azomethine nitrogen atoms forming distorted octahedral geometry around the metal ions. The ESR spectra of copper(II) complexes (3) and (4) showed an axial symmetry with g||>gâ¥>ge, indicating distorted octahedral structure and presence of the unpaired electron in d(x2ây2) orbital. The microbicide studies of the ligand and its metal complexes (2), (3), (4), (5), (8), (11) and (13) showed that, all these complexes exhibit moderate to mild inhibitory effects on B. subtilis, E. coli while complexes (2), (3), (4) and (13) exhibit moderate to mild inhibitory effects on A. niger. Keywords: Hexadentate, Hydrazone, Antipyrine, ESR, Adipohydrazide, Microbicidehttp://www.sciencedirect.com/science/article/pii/S2314853516302153 |
| spellingShingle | Fathy A. El-Saied Mohamad M.E. Shakdofa Abdou S. El Tabl Mokhles M. Abd-Elzaher Nagy Morsy Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II), Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial evaluation Beni-Suef University Journal of Basic and Applied Sciences |
| title | Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II), Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial evaluation |
| title_full | Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II), Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial evaluation |
| title_fullStr | Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II), Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial evaluation |
| title_full_unstemmed | Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II), Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial evaluation |
| title_short | Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II), Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial evaluation |
| title_sort | coordination versatility of n2o4 polydentate hydrazonic ligand in zn ii cu ii ni ii co ii mn ii and pd ii complexes and antimicrobial evaluation |
| url | http://www.sciencedirect.com/science/article/pii/S2314853516302153 |
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