Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants

The identification of immune correlates of protection in humans would inform on the design and development of tuberculosis vaccine candidates. In this work, authors examine samples collected from South African infants, to determine whether the correlates of risk of tuberculosis disease, previously i...

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Bibliographic Details
Main Authors: Iman Satti, Rachel E. Wittenberg, Shuailin Li, Stephanie A. Harris, Rachel Tanner, Deniz Cizmeci, Ashley Jacobs, Nicola Williams, Humphrey Mulenga, Helen A. Fletcher, Thomas J. Scriba, Michele Tameris, Mark Hatherill, Helen McShane
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34061-7