PPG Signals-Based Blood-Pressure Estimation Using Grid Search in Hyperparameter Optimization of CNN–LSTM

Researchers commonly use continuous noninvasive blood-pressure measurement (cNIBP) based on photoplethysmography (PPG) signals to monitor blood pressure conveniently. However, the performance of the system still needs to be improved. Accuracy and precision in blood-pressure measurements are critical...

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Main Authors: Nurul Qashri Mahardika T, Yunendah Nur Fuadah, Da Un Jeong, Ki Moo Lim
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/15/2566
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author Nurul Qashri Mahardika T
Yunendah Nur Fuadah
Da Un Jeong
Ki Moo Lim
author_facet Nurul Qashri Mahardika T
Yunendah Nur Fuadah
Da Un Jeong
Ki Moo Lim
author_sort Nurul Qashri Mahardika T
collection DOAJ
description Researchers commonly use continuous noninvasive blood-pressure measurement (cNIBP) based on photoplethysmography (PPG) signals to monitor blood pressure conveniently. However, the performance of the system still needs to be improved. Accuracy and precision in blood-pressure measurements are critical factors in diagnosing and managing patients’ health conditions. Therefore, we propose a convolutional long short-term memory neural network (CNN–LSTM) with grid search ability, which provides a robust blood-pressure estimation system by extracting meaningful information from PPG signals and reducing the complexity of hyperparameter optimization in the proposed model. The multiparameter intelligent monitoring for intensive care III (MIMIC III) dataset obtained PPG and arterial-blood-pressure (ABP) signals. We obtained 75,226 signal segments, with 60,180 signals allocated for training data, 12,030 signals allocated for the validation set, and 15,045 signals allocated for the test data. During training, we applied five-fold cross-validation with a grid-search method to select the best model and determine the optimal hyperparameter settings. The optimized configuration of the CNN–LSTM layers consisted of five convolutional layers, one long short-term memory (LSTM) layer, and two fully connected layers for blood-pressure estimation. This study successfully achieved good accuracy in assessing both systolic blood pressure (SBP) and diastolic blood pressure (DBP) by calculating the standard deviation (SD) and the mean absolute error (MAE), resulting in values of 7.89 ± 3.79 and 5.34 ± 2.89 mmHg, respectively. The optimal configuration of the CNN–LSTM provided satisfactory performance according to the standards set by the British Hypertension Society (BHS), the Association for the Advancement of Medical Instrumentation (AAMI), and the Institute of Electrical and Electronics Engineers (IEEE) for blood-pressure monitoring devices.
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spelling doaj.art-fe800a4dca8040efa201082a9a7ddf252023-11-18T22:47:14ZengMDPI AGDiagnostics2075-44182023-08-011315256610.3390/diagnostics13152566PPG Signals-Based Blood-Pressure Estimation Using Grid Search in Hyperparameter Optimization of CNN–LSTMNurul Qashri Mahardika T0Yunendah Nur Fuadah1Da Un Jeong2Ki Moo Lim3Computational Medicine Lab, Department of IT Convergence Engineering, Kumoh National Institute of Technology, Gumi 39177, Gyeongbuk, Republic of KoreaComputational Medicine Lab, Department of IT Convergence Engineering, Kumoh National Institute of Technology, Gumi 39177, Gyeongbuk, Republic of KoreaComputational Medicine Lab, Department of IT Convergence Engineering, Kumoh National Institute of Technology, Gumi 39177, Gyeongbuk, Republic of KoreaComputational Medicine Lab, Department of IT Convergence Engineering, Kumoh National Institute of Technology, Gumi 39177, Gyeongbuk, Republic of KoreaResearchers commonly use continuous noninvasive blood-pressure measurement (cNIBP) based on photoplethysmography (PPG) signals to monitor blood pressure conveniently. However, the performance of the system still needs to be improved. Accuracy and precision in blood-pressure measurements are critical factors in diagnosing and managing patients’ health conditions. Therefore, we propose a convolutional long short-term memory neural network (CNN–LSTM) with grid search ability, which provides a robust blood-pressure estimation system by extracting meaningful information from PPG signals and reducing the complexity of hyperparameter optimization in the proposed model. The multiparameter intelligent monitoring for intensive care III (MIMIC III) dataset obtained PPG and arterial-blood-pressure (ABP) signals. We obtained 75,226 signal segments, with 60,180 signals allocated for training data, 12,030 signals allocated for the validation set, and 15,045 signals allocated for the test data. During training, we applied five-fold cross-validation with a grid-search method to select the best model and determine the optimal hyperparameter settings. The optimized configuration of the CNN–LSTM layers consisted of five convolutional layers, one long short-term memory (LSTM) layer, and two fully connected layers for blood-pressure estimation. This study successfully achieved good accuracy in assessing both systolic blood pressure (SBP) and diastolic blood pressure (DBP) by calculating the standard deviation (SD) and the mean absolute error (MAE), resulting in values of 7.89 ± 3.79 and 5.34 ± 2.89 mmHg, respectively. The optimal configuration of the CNN–LSTM provided satisfactory performance according to the standards set by the British Hypertension Society (BHS), the Association for the Advancement of Medical Instrumentation (AAMI), and the Institute of Electrical and Electronics Engineers (IEEE) for blood-pressure monitoring devices.https://www.mdpi.com/2075-4418/13/15/2566photoplethysmography (PPG)blood pressuregrid searchconvolutional neural networklong short-term memory
spellingShingle Nurul Qashri Mahardika T
Yunendah Nur Fuadah
Da Un Jeong
Ki Moo Lim
PPG Signals-Based Blood-Pressure Estimation Using Grid Search in Hyperparameter Optimization of CNN–LSTM
Diagnostics
photoplethysmography (PPG)
blood pressure
grid search
convolutional neural network
long short-term memory
title PPG Signals-Based Blood-Pressure Estimation Using Grid Search in Hyperparameter Optimization of CNN–LSTM
title_full PPG Signals-Based Blood-Pressure Estimation Using Grid Search in Hyperparameter Optimization of CNN–LSTM
title_fullStr PPG Signals-Based Blood-Pressure Estimation Using Grid Search in Hyperparameter Optimization of CNN–LSTM
title_full_unstemmed PPG Signals-Based Blood-Pressure Estimation Using Grid Search in Hyperparameter Optimization of CNN–LSTM
title_short PPG Signals-Based Blood-Pressure Estimation Using Grid Search in Hyperparameter Optimization of CNN–LSTM
title_sort ppg signals based blood pressure estimation using grid search in hyperparameter optimization of cnn lstm
topic photoplethysmography (PPG)
blood pressure
grid search
convolutional neural network
long short-term memory
url https://www.mdpi.com/2075-4418/13/15/2566
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AT daunjeong ppgsignalsbasedbloodpressureestimationusinggridsearchinhyperparameteroptimizationofcnnlstm
AT kimoolim ppgsignalsbasedbloodpressureestimationusinggridsearchinhyperparameteroptimizationofcnnlstm