5-Aza-2′-Deoxycytidine Alters the Methylation Profile of Bortezomib-Resistant U266 Multiple Myeloma Cells and Affects Their Proliferative Potential
Multiple myeloma (MM) is a plasma cell malignancy that accounts for 1% of all cancers and is the second-most-common hematological neoplasm. Bortezomib (BTZ) is a proteasome inhibitor widely implemented in the treatment of MM alone or in combination with other agents. The development of resistance to...
Main Authors: | Karolina Łuczkowska, Piotr Kulig, Klaudia Rusińska, Bartłomiej Baumert, Bogusław Machaliński |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/23/16780 |
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