Ovarian Germ Cell Tumor with Myasthenia Gravis: Co-incidence or a Possible link?
Teratomas are a common form of germ cell tumor. Teratomas are commonly found in the gonadal organs, such as the ovaries and testes. Treatment of choice for ovarian teratomas is complete surgical excision, which exhibits a good prognosis in benign teratomas; however, chemotherapy treatment is needed...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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West Asia Organization for Cancer Prevention
2021-10-01
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| Series: | Asian Pacific Journal of Cancer Care |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcc/article/view/637 |
| _version_ | 1827371017933160448 |
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| author | Jhanzeb Iftikhar Fareeha Sheikh Nazish Khalid Muhammad Abubakar Sarwar Musa Azhar Rizwan Masood Sheikh |
| author_facet | Jhanzeb Iftikhar Fareeha Sheikh Nazish Khalid Muhammad Abubakar Sarwar Musa Azhar Rizwan Masood Sheikh |
| author_sort | Jhanzeb Iftikhar |
| collection | DOAJ |
| description | Teratomas are a common form of germ cell tumor. Teratomas are commonly found in the gonadal organs, such as the ovaries and testes. Treatment of choice for ovarian teratomas is complete surgical excision, which exhibits a good prognosis in benign teratomas; however, chemotherapy treatment is needed for malignant components. Neurological paraneoplastic presentation of gynecological tumors is rare; however, ovarian tumors account for 10% of this presentation. In literature, paraneoplastic limbic encephalitis, anti-N-methyl-D-aspartate receptor encephalitis, and paraneoplastic cerebellar degeneration have been reported in ovarian teratomas and tumors; however, myasthenia gravis has been reported only twice. In both of those cases, manifestation of myasthenia gravis was preceding the diagnosis of ovarian cancer. We describe the first case of a 21-year-old female who presented with new-onset myasthenia gravis after finishing chemotherapy for ovarian teratoma. Another unusual aspect of our case is the rare co-occurrence of gliomatosis peritonei with mature teratoma. |
| first_indexed | 2024-03-08T10:31:03Z |
| format | Article |
| id | doaj.art-fe8dc39a5bbb4de2a3e1b12b606f8a57 |
| institution | Directory Open Access Journal |
| issn | 2588-3682 |
| language | English |
| last_indexed | 2024-03-08T10:31:03Z |
| publishDate | 2021-10-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Care |
| spelling | doaj.art-fe8dc39a5bbb4de2a3e1b12b606f8a572024-01-27T05:09:53ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Care2588-36822021-10-016452552710.31557/apjcc.2021.6.4.525-527637Ovarian Germ Cell Tumor with Myasthenia Gravis: Co-incidence or a Possible link?Jhanzeb Iftikhar0Fareeha SheikhNazish KhalidMuhammad Abubakar SarwarMusa AzharRizwan Masood SheikhShaukat Khanum Memorial Cancer Hospital and Research Center, LahoreTeratomas are a common form of germ cell tumor. Teratomas are commonly found in the gonadal organs, such as the ovaries and testes. Treatment of choice for ovarian teratomas is complete surgical excision, which exhibits a good prognosis in benign teratomas; however, chemotherapy treatment is needed for malignant components. Neurological paraneoplastic presentation of gynecological tumors is rare; however, ovarian tumors account for 10% of this presentation. In literature, paraneoplastic limbic encephalitis, anti-N-methyl-D-aspartate receptor encephalitis, and paraneoplastic cerebellar degeneration have been reported in ovarian teratomas and tumors; however, myasthenia gravis has been reported only twice. In both of those cases, manifestation of myasthenia gravis was preceding the diagnosis of ovarian cancer. We describe the first case of a 21-year-old female who presented with new-onset myasthenia gravis after finishing chemotherapy for ovarian teratoma. Another unusual aspect of our case is the rare co-occurrence of gliomatosis peritonei with mature teratoma.http://www.waocp.com/journal/index.php/apjcc/article/view/637ovarian teratoma, paraneoplastic presentation, myasthenia gravis, gliomatosis peritonei |
| spellingShingle | Jhanzeb Iftikhar Fareeha Sheikh Nazish Khalid Muhammad Abubakar Sarwar Musa Azhar Rizwan Masood Sheikh Ovarian Germ Cell Tumor with Myasthenia Gravis: Co-incidence or a Possible link? Asian Pacific Journal of Cancer Care ovarian teratoma, paraneoplastic presentation, myasthenia gravis, gliomatosis peritonei |
| title | Ovarian Germ Cell Tumor with Myasthenia Gravis: Co-incidence or a Possible link? |
| title_full | Ovarian Germ Cell Tumor with Myasthenia Gravis: Co-incidence or a Possible link? |
| title_fullStr | Ovarian Germ Cell Tumor with Myasthenia Gravis: Co-incidence or a Possible link? |
| title_full_unstemmed | Ovarian Germ Cell Tumor with Myasthenia Gravis: Co-incidence or a Possible link? |
| title_short | Ovarian Germ Cell Tumor with Myasthenia Gravis: Co-incidence or a Possible link? |
| title_sort | ovarian germ cell tumor with myasthenia gravis co incidence or a possible link |
| topic | ovarian teratoma, paraneoplastic presentation, myasthenia gravis, gliomatosis peritonei |
| url | http://www.waocp.com/journal/index.php/apjcc/article/view/637 |
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