Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia Repair
Umbilical hernias in calves occur with relative frequency. Most abdominal surgeries can be performed in cattle using standing sedation and local blocks. Romifidine is widely used in calves, alone or in combination with opioids. Tramadol administered as an intravenous slow injection provided better a...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-03-01
|
| Series: | Animals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2615/13/7/1145 |
| _version_ | 1797608506943078400 |
|---|---|
| author | Giovanna L. Costa Fabio Leonardi Claudia Interlandi Patrizia Licata Ignacio Lizarraga Francesco Macrì Daniele Macrì Vincenzo Ferrantelli Filippo Spadola |
| author_facet | Giovanna L. Costa Fabio Leonardi Claudia Interlandi Patrizia Licata Ignacio Lizarraga Francesco Macrì Daniele Macrì Vincenzo Ferrantelli Filippo Spadola |
| author_sort | Giovanna L. Costa |
| collection | DOAJ |
| description | Umbilical hernias in calves occur with relative frequency. Most abdominal surgeries can be performed in cattle using standing sedation and local blocks. Romifidine is widely used in calves, alone or in combination with opioids. Tramadol administered as an intravenous slow injection provided better analgesia than an IV bolus in cows. The aim of the present study was to compare the response to surgical stimulus, and sedative effects of tramadol administered intravenously either as a bolus or a slow injection in romifidinesedated calves. Twenty Frisian calves undergoing umbilical hernia repair received romifidine (0.08 mg/kg IM; time 0) followed by tramadol (1 mg/kg IV) 5 min later either as a bolus (<i>n</i> = 10, B group) or a slow injection over 10 min (<i>n</i> = 10, SI group). Surgical area was infiltrated with lidocaine (4 mg/kg). Heart rate (HR), respiratory rate (RR), systolic, dyastolic and mean arterial pressure (SAP, DAP, MAP), sedation scores and response to surgical stimulus were recorded for up to 55 min. After the calves recovered a standing position, postoperative pain scores were assessed for up to 50 min. Sedation scores were significantly higher in the SI group than in the B group at 55 min (<i>p</i> < 0.05). HR, RR, SAP and response to surgical stimulus were significantly higher in the B group than in the SI group (<i>p</i> < 0.05). No significant differences were recorded in postoperative pain scores between groups (<i>p</i> > 0.05). Romifidine IM followed by intravenous tramadol, as a bolus or slow injection and local infiltration with lidocaine provided adequate sedation and analgesia in calves undergoing umbilical hernia repair. |
| first_indexed | 2024-03-11T05:44:24Z |
| format | Article |
| id | doaj.art-fe8e57b712d447f29790d7feafa20581 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T05:44:24Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-fe8e57b712d447f29790d7feafa205812023-11-17T16:13:25ZengMDPI AGAnimals2076-26152023-03-01137114510.3390/ani13071145Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia RepairGiovanna L. Costa0Fabio Leonardi1Claudia Interlandi2Patrizia Licata3Ignacio Lizarraga4Francesco Macrì5Daniele Macrì6Vincenzo Ferrantelli7Filippo Spadola8Department of Veterinary Sciences, University of Messina, Via Palatucci Annunziata, 98168 Messina, ItalyDepartment of Veterinary Science, University of Parma, Via del Taglio 10, 43126 Parma, ItalyDepartment of Veterinary Sciences, University of Messina, Via Palatucci Annunziata, 98168 Messina, ItalyDepartment of Veterinary Sciences, University of Messina, Via Palatucci Annunziata, 98168 Messina, ItalyAgResearch Limited, Grasslands Research Centre, Palmerston North 4442, New ZealandDepartment of Veterinary Sciences, University of Messina, Via Palatucci Annunziata, 98168 Messina, ItalyZooprophylactic Institute, Via Gino Marinuzzi 3, 90100 Palermo, ItalyZooprophylactic Institute, Via Gino Marinuzzi 3, 90100 Palermo, ItalyDepartment of Veterinary Sciences, University of Messina, Via Palatucci Annunziata, 98168 Messina, ItalyUmbilical hernias in calves occur with relative frequency. Most abdominal surgeries can be performed in cattle using standing sedation and local blocks. Romifidine is widely used in calves, alone or in combination with opioids. Tramadol administered as an intravenous slow injection provided better analgesia than an IV bolus in cows. The aim of the present study was to compare the response to surgical stimulus, and sedative effects of tramadol administered intravenously either as a bolus or a slow injection in romifidinesedated calves. Twenty Frisian calves undergoing umbilical hernia repair received romifidine (0.08 mg/kg IM; time 0) followed by tramadol (1 mg/kg IV) 5 min later either as a bolus (<i>n</i> = 10, B group) or a slow injection over 10 min (<i>n</i> = 10, SI group). Surgical area was infiltrated with lidocaine (4 mg/kg). Heart rate (HR), respiratory rate (RR), systolic, dyastolic and mean arterial pressure (SAP, DAP, MAP), sedation scores and response to surgical stimulus were recorded for up to 55 min. After the calves recovered a standing position, postoperative pain scores were assessed for up to 50 min. Sedation scores were significantly higher in the SI group than in the B group at 55 min (<i>p</i> < 0.05). HR, RR, SAP and response to surgical stimulus were significantly higher in the B group than in the SI group (<i>p</i> < 0.05). No significant differences were recorded in postoperative pain scores between groups (<i>p</i> > 0.05). Romifidine IM followed by intravenous tramadol, as a bolus or slow injection and local infiltration with lidocaine provided adequate sedation and analgesia in calves undergoing umbilical hernia repair.https://www.mdpi.com/2076-2615/13/7/1145calvesumbilical herniaromifidinetramadolslow infusionpain |
| spellingShingle | Giovanna L. Costa Fabio Leonardi Claudia Interlandi Patrizia Licata Ignacio Lizarraga Francesco Macrì Daniele Macrì Vincenzo Ferrantelli Filippo Spadola Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia Repair Animals calves umbilical hernia romifidine tramadol slow infusion pain |
| title | Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia Repair |
| title_full | Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia Repair |
| title_fullStr | Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia Repair |
| title_full_unstemmed | Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia Repair |
| title_short | Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia Repair |
| title_sort | tramadol administered intravenously either as a bolus or a slow injection in pain management of romifidine sedated calves undergoing umbilical hernia repair |
| topic | calves umbilical hernia romifidine tramadol slow infusion pain |
| url | https://www.mdpi.com/2076-2615/13/7/1145 |
| work_keys_str_mv | AT giovannalcosta tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair AT fabioleonardi tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair AT claudiainterlandi tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair AT patrizialicata tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair AT ignaciolizarraga tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair AT francescomacri tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair AT danielemacri tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair AT vincenzoferrantelli tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair AT filippospadola tramadoladministeredintravenouslyeitherasabolusoraslowinjectioninpainmanagementofromifidinesedatedcalvesundergoingumbilicalherniarepair |