Behind the Curtain: In Silico and In Vitro Experiments Brought to Light New Insights into the Anticryptococcal Action of Synthetic Peptides

Behind the Curtain: In Silico and In Vitro Experiments Brought to Light New Insights into the Anticryptococcal Action of Synthetic Peptides

<i>Cryptococcus neoformans</i> is the pathogen responsible for cryptococcal pneumonia and meningitis, mainly affecting patients with suppressed immune systems. We have previously revealed the mechanism of anticryptococcal action of synthetic antimicrobial peptides (SAMPs). In this study,...

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Bibliographic Details
Main Authors: Tawanny K. B. Aguiar, Nilton A. S. Neto, Romério R. S. Silva, Cleverson D. T. Freitas, Felipe P. Mesquita, Luciana M. R. Alencar, Ralph Santos-Oliveira, Gustavo H. Goldman, Pedro F. N. Souza
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Antibiotics
Subjects:
redox system
<i>Cryptococcus neoformans</i>
ROS metabolism
ergosterol
synthetic antimicrobial peptides
Online Access:https://www.mdpi.com/2079-6382/12/1/153

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