Post-ruminal delivery systems

Livestock industry and organization for animal wellfare underlie the need for drug and nutrient delivery systems for ruminants that protect active ingredients from ruminal fermentation. To deliver drugs or nutrients directly to the small intestine for absorption, therapeutical systems must meet the...

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Main Authors: Miloslava Rabišková, Jiří Třináctý, Tomáš Sýkora, Petr Doležal
Format: Article
Language:English
Published: Mendel University Press 2004-01-01
Series:Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis
Subjects:
Online Access:https://acta.mendelu.cz/52/2/0143/
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author Miloslava Rabišková
Jiří Třináctý
Tomáš Sýkora
Petr Doležal
author_facet Miloslava Rabišková
Jiří Třináctý
Tomáš Sýkora
Petr Doležal
author_sort Miloslava Rabišková
collection DOAJ
description Livestock industry and organization for animal wellfare underlie the need for drug and nutrient delivery systems for ruminants that protect active ingredients from ruminal fermentation. To deliver drugs or nutrients directly to the small intestine for absorption, therapeutical systems must meet the safety and cost criteria. An effective post-ruminal delivery system is a prerequisite to implement some significant advances in animal nutrition and health in ruminants. Comparing with the products developed for human use, cost constraints have impeded the development of effective post-ruminal delivery systems and rumenstable products. This article outlines physiological and technical considerations encountered in the design of effective post-ruminal delivery systems. The requirements and formulation of a pH-dependent rumen stable coating systems and possible future developments will be discussed.
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spelling doaj.art-fe8f0add56404331ad8148817b1425772022-12-22T02:56:49ZengMendel University PressActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis1211-85162464-83102004-01-0152214314810.11118/actaun200452020143Post-ruminal delivery systemsMiloslava Rabišková0Jiří Třináctý1Tomáš Sýkora2Petr Doležal3Ústav technologie léků, Veterinární a farmaceutická univerzita Brno, Palackého 1-3, 61242 Brno, Česká republikaVýzkumný ústav chovu skotu, s.r.o., Vídeňská 699, 69123 Pohořelice, Česká republikaÚstav technologie léků, Veterinární a farmaceutická univerzita Brno, Palackého 1-3, 61242 Brno, Česká republikaÚstav výživy a krmení hospodářských zvířat, Mendelova zemědělská a lesnická univerzita v Brně, Zemědělská 1, 613 00 Brno, Česká republikaLivestock industry and organization for animal wellfare underlie the need for drug and nutrient delivery systems for ruminants that protect active ingredients from ruminal fermentation. To deliver drugs or nutrients directly to the small intestine for absorption, therapeutical systems must meet the safety and cost criteria. An effective post-ruminal delivery system is a prerequisite to implement some significant advances in animal nutrition and health in ruminants. Comparing with the products developed for human use, cost constraints have impeded the development of effective post-ruminal delivery systems and rumenstable products. This article outlines physiological and technical considerations encountered in the design of effective post-ruminal delivery systems. The requirements and formulation of a pH-dependent rumen stable coating systems and possible future developments will be discussed.https://acta.mendelu.cz/52/2/0143/ruminantamino acid deficiencyactive ingredient deliveryrumenstable product
spellingShingle Miloslava Rabišková
Jiří Třináctý
Tomáš Sýkora
Petr Doležal
Post-ruminal delivery systems
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis
ruminant
amino acid deficiency
active ingredient delivery
rumenstable product
title Post-ruminal delivery systems
title_full Post-ruminal delivery systems
title_fullStr Post-ruminal delivery systems
title_full_unstemmed Post-ruminal delivery systems
title_short Post-ruminal delivery systems
title_sort post ruminal delivery systems
topic ruminant
amino acid deficiency
active ingredient delivery
rumenstable product
url https://acta.mendelu.cz/52/2/0143/
work_keys_str_mv AT miloslavarabiskova postruminaldeliverysystems
AT jiritrinacty postruminaldeliverysystems
AT tomassykora postruminaldeliverysystems
AT petrdolezal postruminaldeliverysystems