Serum Zinc Concentration Could Predict Bone Mineral Density and Protect Osteoporosis in Healthy Men
Background: A growing body of investigations demonstrated the essence role of zinc on growing and maintaining bone tis¬sue .The idea that zinc could enhance bone content and adjourn or prevent osteoporosis in men, has been experimented as a hy¬pothesis. Methods: Six hundred healthy men (age 20-69 yr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2007-08-01
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| Series: | Iranian Journal of Public Health |
| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/3679.pdf&manuscript_id=3679 |
| _version_ | 1818900141222920192 |
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| author | E Mir A Hossein-nezhad A Bahrami MR Bekheirnia E Javadi A Afshar Naderi B Larijani |
| author_facet | E Mir A Hossein-nezhad A Bahrami MR Bekheirnia E Javadi A Afshar Naderi B Larijani |
| author_sort | E Mir |
| collection | DOAJ |
| description | Background: A growing body of investigations demonstrated the essence role of zinc on growing and maintaining bone tis¬sue .The idea that zinc could enhance bone content and adjourn or prevent osteoporosis in men, has been experimented as a hy¬pothesis. Methods: Six hundred healthy men (age 20-69 yr) through Iranian Multicenter Osteoporosis Study (IMOS) which is a na¬tional project running in 5 provinces in Iran for prevention and treatment of osteoporosis was selected via a cluster random sam¬pling and enrolled the study. Bone Mineral Density was measured by biphotonic absorptimetry DEXA for hip and lum¬bar spine. Zinc morning serum concentration was determined by atomic absorption spectrometry. SPSS 11.5 was used for data analysis. Body Mass Index (BMI) has been calculated by Weight (kg)/Height (meter)2 for each person Results: The mean age was 40.83±15.06 yr .Mean BMI was 24.79±3.94 kg/m2, overlay 27.3% were smoking, 12.5% had regu¬lar physical activities three times a week and 12.2% had a history of renal stone. Among them 30.1% had zinc deple¬tion, 56.8% normal range and 13.1% had serum zinc excess. 57.1% of individuals over 40 yr with hip osteoporosis were zinc deficient whereas 22.1% of them with normal BMD had this deficiency (P< 0.001). Conclusion: It is concluded that zinc has a positive association with BMD in men over 40 yr and zinc deficiency is more com¬mon in osteoporotic individuals. |
| first_indexed | 2024-12-19T19:59:08Z |
| format | Article |
| id | doaj.art-fe981edaa8a043448ca6a585c14f6f18 |
| institution | Directory Open Access Journal |
| issn | 2251-6085 |
| language | English |
| last_indexed | 2024-12-19T19:59:08Z |
| publishDate | 2007-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Public Health |
| spelling | doaj.art-fe981edaa8a043448ca6a585c14f6f182022-12-21T20:07:43ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852007-08-013036Serum Zinc Concentration Could Predict Bone Mineral Density and Protect Osteoporosis in Healthy MenE MirA Hossein-nezhadA BahramiMR BekheirniaE JavadiA Afshar NaderiB LarijaniBackground: A growing body of investigations demonstrated the essence role of zinc on growing and maintaining bone tis¬sue .The idea that zinc could enhance bone content and adjourn or prevent osteoporosis in men, has been experimented as a hy¬pothesis. Methods: Six hundred healthy men (age 20-69 yr) through Iranian Multicenter Osteoporosis Study (IMOS) which is a na¬tional project running in 5 provinces in Iran for prevention and treatment of osteoporosis was selected via a cluster random sam¬pling and enrolled the study. Bone Mineral Density was measured by biphotonic absorptimetry DEXA for hip and lum¬bar spine. Zinc morning serum concentration was determined by atomic absorption spectrometry. SPSS 11.5 was used for data analysis. Body Mass Index (BMI) has been calculated by Weight (kg)/Height (meter)2 for each person Results: The mean age was 40.83±15.06 yr .Mean BMI was 24.79±3.94 kg/m2, overlay 27.3% were smoking, 12.5% had regu¬lar physical activities three times a week and 12.2% had a history of renal stone. Among them 30.1% had zinc deple¬tion, 56.8% normal range and 13.1% had serum zinc excess. 57.1% of individuals over 40 yr with hip osteoporosis were zinc deficient whereas 22.1% of them with normal BMD had this deficiency (P< 0.001). Conclusion: It is concluded that zinc has a positive association with BMD in men over 40 yr and zinc deficiency is more com¬mon in osteoporotic individuals.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/3679.pdf&manuscript_id=3679 |
| spellingShingle | E Mir A Hossein-nezhad A Bahrami MR Bekheirnia E Javadi A Afshar Naderi B Larijani Serum Zinc Concentration Could Predict Bone Mineral Density and Protect Osteoporosis in Healthy Men Iranian Journal of Public Health |
| title | Serum Zinc Concentration Could Predict Bone Mineral Density and Protect Osteoporosis in Healthy Men |
| title_full | Serum Zinc Concentration Could Predict Bone Mineral Density and Protect Osteoporosis in Healthy Men |
| title_fullStr | Serum Zinc Concentration Could Predict Bone Mineral Density and Protect Osteoporosis in Healthy Men |
| title_full_unstemmed | Serum Zinc Concentration Could Predict Bone Mineral Density and Protect Osteoporosis in Healthy Men |
| title_short | Serum Zinc Concentration Could Predict Bone Mineral Density and Protect Osteoporosis in Healthy Men |
| title_sort | serum zinc concentration could predict bone mineral density and protect osteoporosis in healthy men |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/3679.pdf&manuscript_id=3679 |
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