ApoE isoform does not influence skeletal muscle regeneration in adult mice

ApoE isoform does not influence skeletal muscle regeneration in adult mice

Introduction: Apolipoprotein E (ApoE) has been shown to be necessary for proper skeletal muscle regeneration. Consistent with this finding, single-cell RNA-sequencing analyses of skeletal muscle stem cells (MuSCs) revealed that Apoe is a top marker of quiescent MuSCs that is downregulated upon activ...

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Bibliographic Details
Main Authors: Benjamin I. Burke, Jensen Goh, Fatmah A. Albathi, Taylor R. Valentino, Georgia L. Nolt, Jai K. Joshi, Cory M. Dungan, Lance A. Johnson, Yuan Wen, Ahmed Ismaeel, John J. McCarthy
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Physiology
Subjects:
APOE
regeneration
satellite cells
MuSCs
myogenesis
proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1302695/full

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