Methods for Detection of Bacterial Endotoxin in Critical Care Medicine

Dedicated to reviewing the methods for detecting bacterial endotoxin in aqueous solutions and biological fluids, this review is focused on determining the content of endotoxin as a clinically relevant biomarker of sepsis caused by Gram-negative bacteria. The advantages and disadvantages of each meth...

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Main Authors: M. N. Kopitsyna, A. S. Morozov, I. V. Bessonov, V. M. Pisarev
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2018-01-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1628
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author M. N. Kopitsyna
A. S. Morozov
I. V. Bessonov
V. M. Pisarev
author_facet M. N. Kopitsyna
A. S. Morozov
I. V. Bessonov
V. M. Pisarev
author_sort M. N. Kopitsyna
collection DOAJ
description Dedicated to reviewing the methods for detecting bacterial endotoxin in aqueous solutions and biological fluids, this review is focused on determining the content of endotoxin as a clinically relevant biomarker of sepsis caused by Gram-negative bacteria. The advantages and disadvantages of each method are described, and the characteristics of test systems currently used in clinical practice are listed and compared.
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publishDate 2018-01-01
publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
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spelling doaj.art-fea6d3b4a79c40a09958b76a57bc62c12023-03-13T09:32:55ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102018-01-0113510912010.15360/1813-9779-2017-5-109-1201586Methods for Detection of Bacterial Endotoxin in Critical Care MedicineM. N. Kopitsyna0A. S. Morozov1I. V. Bessonov2V. M. Pisarev3АО Перспективные медицинские технологииАО Перспективные медицинские технологииАО Перспективные медицинские технологииНИИ общей реаниматологии им. В. А. Неговского ФНКЦ реаниматологии и реабилитологии; Центральный научно-исследовательский институт эпидемиологии РоспотребнадзораDedicated to reviewing the methods for detecting bacterial endotoxin in aqueous solutions and biological fluids, this review is focused on determining the content of endotoxin as a clinically relevant biomarker of sepsis caused by Gram-negative bacteria. The advantages and disadvantages of each method are described, and the characteristics of test systems currently used in clinical practice are listed and compared.https://www.reanimatology.com/rmt/article/view/1628бактериальный эндотоксинлипополисахаридграмотрицательные бактериисепсислал-тестанализ активности эндотоксинаметод активированных частиц
spellingShingle M. N. Kopitsyna
A. S. Morozov
I. V. Bessonov
V. M. Pisarev
Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
Общая реаниматология
бактериальный эндотоксин
липополисахарид
грамотрицательные бактерии
сепсис
лал-тест
анализ активности эндотоксина
метод активированных частиц
title Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_full Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_fullStr Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_full_unstemmed Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_short Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_sort methods for detection of bacterial endotoxin in critical care medicine
topic бактериальный эндотоксин
липополисахарид
грамотрицательные бактерии
сепсис
лал-тест
анализ активности эндотоксина
метод активированных частиц
url https://www.reanimatology.com/rmt/article/view/1628
work_keys_str_mv AT mnkopitsyna methodsfordetectionofbacterialendotoxinincriticalcaremedicine
AT asmorozov methodsfordetectionofbacterialendotoxinincriticalcaremedicine
AT ivbessonov methodsfordetectionofbacterialendotoxinincriticalcaremedicine
AT vmpisarev methodsfordetectionofbacterialendotoxinincriticalcaremedicine