Primary Papillary Serous Carcinoma of the Peritoneum, A Retrospective Analysis of 18 Cases
OBJECTIVE: Primary papillary serous carcinoma of the peritoneum (PPSCP) is an uncommon tumor. The aim of this study was to review of the patients with PPSCP. STUDY DESIGN: 18 women with PPSCP in gynecologic oncology clinic between 1995 and 2005 were retrospectively reviewed. RESULTS: At diagnose, on...
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| Format: | Article |
| Language: | English |
| Published: |
Medical Network
2006-08-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/586 |
| _version_ | 1828024703700172800 |
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| author | Taner Turan Şadıman Altınbaş Nurettin Boran Gökhan Tulunay Reyhan Öcalan Figen Günday Deniz Çavuşoğlu Faruk Köse |
| author_facet | Taner Turan Şadıman Altınbaş Nurettin Boran Gökhan Tulunay Reyhan Öcalan Figen Günday Deniz Çavuşoğlu Faruk Köse |
| author_sort | Taner Turan |
| collection | DOAJ |
| description | OBJECTIVE: Primary papillary serous carcinoma of the peritoneum (PPSCP) is an uncommon tumor. The aim of this study was to review of the patients with PPSCP.
STUDY DESIGN: 18 women with PPSCP in gynecologic oncology clinic between 1995 and 2005 were retrospectively reviewed.
RESULTS: At diagnose, one patient (5.5 %) had stage IV and other patients (94.5 %) were IIIC. Six patients received neoadjuvant chemotherapy (paclitaxel/platinum in 5 patients and cyclophosphamide/platinum in the other). Initial or interval optimal/suboptimal debulking surgery was performed in all patients. After surgery, all of the patients received adjuvant chemotherapy including paclitaxel/platinum (n=16) and cyclophosphamide/platinum (n=2). In 6 months after adjuvant chemotherapy, persistent, progressive or recurrence disease was detected in 8 patients (44.4%). In 9 patients (50%) recurrence was detected after 6 months. Clinical complete response to chemotherapy was 55.5%. Survival rate was 90%.
CONCLUSION: PPSPC are frequently indistinguishable from advanced serous papillary carcinoma of the ovary. The treatment choice is optimal cytoreductive surgery with adjuvant chemotherapy, but although the radical treatment is used the survival rate is poor. |
| first_indexed | 2024-04-10T12:49:03Z |
| format | Article |
| id | doaj.art-fea716d667a646d29a5032aff7f97c4b |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T12:49:03Z |
| publishDate | 2006-08-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-fea716d667a646d29a5032aff7f97c4b2023-02-15T16:13:56ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512006-08-01122520Primary Papillary Serous Carcinoma of the Peritoneum, A Retrospective Analysis of 18 CasesTaner Turan0Şadıman Altınbaş1Nurettin Boran2Gökhan Tulunay3Reyhan Öcalan4Figen Günday5Deniz Çavuşoğlu6Faruk Köse7Ankara Etlik Maternity and Women’s Health Teaching Hospital Gynecologic Oncology Clinic, AnkaraAnkara Etlik Maternity and Women’s Health Teaching Hospital Gynecologic Oncology Clinic, AnkaraAnkara Etlik Maternity and Women’s Health Teaching Hospital Gynecologic Oncology Clinic, AnkaraAnkara Etlik Maternity and Women’s Health Teaching Hospital Gynecologic Oncology Clinic, AnkaraAnkara Etlik Maternity and Women’s Health Teaching Hospital Gynecologic Oncology Clinic, AnkaraAnkara Etlik Maternity and Women’s Health Teaching Hospital Gynecologic Oncology Clinic, AnkaraAnkara Etlik Maternity and Women’s Health Teaching Hospital Pathology Division, AnkaraAnkara Etlik Maternity and Women’s Health Teaching Hospital Gynecologic Oncology Clinic, AnkaraOBJECTIVE: Primary papillary serous carcinoma of the peritoneum (PPSCP) is an uncommon tumor. The aim of this study was to review of the patients with PPSCP. STUDY DESIGN: 18 women with PPSCP in gynecologic oncology clinic between 1995 and 2005 were retrospectively reviewed. RESULTS: At diagnose, one patient (5.5 %) had stage IV and other patients (94.5 %) were IIIC. Six patients received neoadjuvant chemotherapy (paclitaxel/platinum in 5 patients and cyclophosphamide/platinum in the other). Initial or interval optimal/suboptimal debulking surgery was performed in all patients. After surgery, all of the patients received adjuvant chemotherapy including paclitaxel/platinum (n=16) and cyclophosphamide/platinum (n=2). In 6 months after adjuvant chemotherapy, persistent, progressive or recurrence disease was detected in 8 patients (44.4%). In 9 patients (50%) recurrence was detected after 6 months. Clinical complete response to chemotherapy was 55.5%. Survival rate was 90%. CONCLUSION: PPSPC are frequently indistinguishable from advanced serous papillary carcinoma of the ovary. The treatment choice is optimal cytoreductive surgery with adjuvant chemotherapy, but although the radical treatment is used the survival rate is poor.http://gorm.com.tr/index.php/GORM/article/view/586P rimary Papillary Serous Carcinoma, Peritoneum |
| spellingShingle | Taner Turan Şadıman Altınbaş Nurettin Boran Gökhan Tulunay Reyhan Öcalan Figen Günday Deniz Çavuşoğlu Faruk Köse Primary Papillary Serous Carcinoma of the Peritoneum, A Retrospective Analysis of 18 Cases Gynecology Obstetrics & Reproductive Medicine P rimary Papillary Serous Carcinoma, Peritoneum |
| title | Primary Papillary Serous Carcinoma of the Peritoneum, A Retrospective Analysis of 18 Cases |
| title_full | Primary Papillary Serous Carcinoma of the Peritoneum, A Retrospective Analysis of 18 Cases |
| title_fullStr | Primary Papillary Serous Carcinoma of the Peritoneum, A Retrospective Analysis of 18 Cases |
| title_full_unstemmed | Primary Papillary Serous Carcinoma of the Peritoneum, A Retrospective Analysis of 18 Cases |
| title_short | Primary Papillary Serous Carcinoma of the Peritoneum, A Retrospective Analysis of 18 Cases |
| title_sort | primary papillary serous carcinoma of the peritoneum a retrospective analysis of 18 cases |
| topic | P rimary Papillary Serous Carcinoma, Peritoneum |
| url | http://gorm.com.tr/index.php/GORM/article/view/586 |
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