The effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid-19
Background and Objective: Numerous studies have shown the anti-inflammatory, antimicrobial, anti-allergic, anti-cancer, anti-spasm, analgesic and wound healing effects of chamomile (Matricaria chamomile). In this study, the effect of aqueous and ethanolic extracts of chamomile on the vital activity...
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| Format: | Article |
| Language: | fas |
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Shahed University
2023-02-01
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| Series: | دانشور پزشکی |
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| Online Access: | http://daneshvarmed.shahed.ac.ir/article_4000_5291ec19cbfc6da99b2a5bb78d4d735f.pdf |
| _version_ | 1797840049547509760 |
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| author | Rasoul Rashidi Tooba Ghazanfari Tayebeh Radjabian Ensie Sadat Mirsharif |
| author_facet | Rasoul Rashidi Tooba Ghazanfari Tayebeh Radjabian Ensie Sadat Mirsharif |
| author_sort | Rasoul Rashidi |
| collection | DOAJ |
| description | Background and Objective: Numerous studies have shown the anti-inflammatory, antimicrobial, anti-allergic, anti-cancer, anti-spasm, analgesic and wound healing effects of chamomile (Matricaria chamomile). In this study, the effect of aqueous and ethanolic extracts of chamomile on the vital activity of cultured leukocytes of patients with covid-19 was investigated.
Materials and Methods: After preparation of aqueous and ethanolic extracts of chamomile, peripheral blood mononuclear cells (PBMC) of patients with covid-19 with doses of 200, 300, 400 and 500 micrograms/ml of ethanolic extract of chamomile and doses of 400, 500, 600 and 700 µg/ml chamomile aqueous extract were treated. After 24 hours, the vital activity of PBMCs was measured by MTT method. To analyze the findings, one-way analysis of variance was used in SPSS software version 24. P<0.05 was considered significant.
Results: In the current research, chamomile ethanol extract in doses of 500 micrograms/ml and aqueous extract in doses of 600 and 700 micrograms/ml led to a significant decrease in the vital activity of peripheral blood mononuclear cells compared to the control group.
Conclusion: Aqueous and ethanol extracts of chamomile significantly decrease the vital activity of peripheral blood mononuclear cells; This decrease in vital activity is dose-dependent, and with increasing dose, a decrease in vital activity is observed.
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| first_indexed | 2024-04-09T16:06:57Z |
| format | Article |
| id | doaj.art-fea83e1333104fc281637b634f12b777 |
| institution | Directory Open Access Journal |
| issn | 2716-9731 |
| language | fas |
| last_indexed | 2024-04-09T16:06:57Z |
| publishDate | 2023-02-01 |
| publisher | Shahed University |
| record_format | Article |
| series | دانشور پزشکی |
| spelling | doaj.art-fea83e1333104fc281637b634f12b7772023-04-25T05:29:29ZfasShahed Universityدانشور پزشکی2716-97312023-02-013061910.22070/DANESHMED.2023.17141.1304The effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid-19Rasoul Rashidi0Tooba Ghazanfari1Tayebeh Radjabian2Ensie Sadat Mirsharif31. Department of immunology, Faculty of Medicine, Shahed University, Tehran, Iran2. Immunoregulation Research Center, Shahed University, Tehran, Iran2. Immunoregulation Research Center, Shahed University, Tehran, Iran2. Immunoregulation Research Center, Shahed University, Tehran, IranBackground and Objective: Numerous studies have shown the anti-inflammatory, antimicrobial, anti-allergic, anti-cancer, anti-spasm, analgesic and wound healing effects of chamomile (Matricaria chamomile). In this study, the effect of aqueous and ethanolic extracts of chamomile on the vital activity of cultured leukocytes of patients with covid-19 was investigated. Materials and Methods: After preparation of aqueous and ethanolic extracts of chamomile, peripheral blood mononuclear cells (PBMC) of patients with covid-19 with doses of 200, 300, 400 and 500 micrograms/ml of ethanolic extract of chamomile and doses of 400, 500, 600 and 700 µg/ml chamomile aqueous extract were treated. After 24 hours, the vital activity of PBMCs was measured by MTT method. To analyze the findings, one-way analysis of variance was used in SPSS software version 24. P<0.05 was considered significant. Results: In the current research, chamomile ethanol extract in doses of 500 micrograms/ml and aqueous extract in doses of 600 and 700 micrograms/ml led to a significant decrease in the vital activity of peripheral blood mononuclear cells compared to the control group. Conclusion: Aqueous and ethanol extracts of chamomile significantly decrease the vital activity of peripheral blood mononuclear cells; This decrease in vital activity is dose-dependent, and with increasing dose, a decrease in vital activity is observed. http://daneshvarmed.shahed.ac.ir/article_4000_5291ec19cbfc6da99b2a5bb78d4d735f.pdfchamomilecovid-19 |
| spellingShingle | Rasoul Rashidi Tooba Ghazanfari Tayebeh Radjabian Ensie Sadat Mirsharif The effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid-19 دانشور پزشکی chamomile covid-19 |
| title | The effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid-19 |
| title_full | The effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid-19 |
| title_fullStr | The effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid-19 |
| title_full_unstemmed | The effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid-19 |
| title_short | The effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid-19 |
| title_sort | effect of aqueous and ethanolic extracts of chamomile on the vital activity of peripheral blood leukocytes of patients with covid 19 |
| topic | chamomile covid-19 |
| url | http://daneshvarmed.shahed.ac.ir/article_4000_5291ec19cbfc6da99b2a5bb78d4d735f.pdf |
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