Low Level of Serum Immunoglobulin G Is Beneficial to Clinical Cure Obtained With Pegylated Interferon Therapy in Inactive Surface Antigen Carriers

Low Level of Serum Immunoglobulin G Is Beneficial to Clinical Cure Obtained With Pegylated Interferon Therapy in Inactive Surface Antigen Carriers

PurposeOur recent study showed a high rate of HBsAg clearance in inactive HBsAg carriers (IHCs) treated with pegylated IFN (PEG-IFN). To better understand the immune-mediated component of HBsAg clearance, this study investigated the role of serum immunoglobulin G (IgG) and its subclasses in predicti...

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Bibliographic Details
Main Authors: Hong Li, Xiao Lin, Lili Liu, Ling Qin, Yanhong Zheng, Xiaohui Liu, Xinhuan Wei, Shan Liang, Yali Liu, Jing Zhang, Xinyue Chen, Zhenhuan Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
inactive HBsAg carriers
HBsAg clearance
pegylated interferon
lgG
predictor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.864354/full

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