circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression

circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression

In recent years, circular RNAs (circRNAs) have been shown to have critical regulatory roles in the resistance to anti-cancer drugs. However, the contributions of circRNAs to sorafenib resistance in hepatocellular carcinoma (HCC) remain largely unknown. The present study aims to explore the involveme...

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Bibliographic Details
Main Authors: Cheng Yang, Zhitao Dong, Han Hong, Binghua Dai, Feihong Song, Li Geng, Jiongjiong Lu, Jiamei Yang, Minhui Xu, Chengjun Sui
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
circRNAs
circFN1
microR-1205
E2F1
hepatocellular carcinoma
sorafenib
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120302699

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