The implication of adenosine receptor expression in prediction of methotrexate clinical response in Egyptian rheumatoid arthritis patients

The implication of adenosine receptor expression in prediction of methotrexate clinical response in Egyptian rheumatoid arthritis patients

Abstract Background Adenosine signaling is now an accepted explanation for the therapeutic mechanism of Methotrexate (MTX) in rheumatoid arthritis (RA). Adenosine receptors categorized into four subclasses: adenosine A1 receptor (ADORA1), adenosine 2a receptor (ADORA2a), adenosine 2b receptor (ADORA...

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Main Authors: Nivine Fathi Darwish, Samar Abd Alhamed Tabra, Nivin Naeem Baiomy, Heba A. Mahmoud, Reham A. Mariah, Shymaa Ahmed Hablas
Format: Article
Language:English
Published: SpringerOpen 2022-02-01
Series:Egyptian Rheumatology and Rehabilitation
Subjects:
Adenosine receptor
Rheumatoid arthritis
MTX response
Inflammatory mediators
Online Access:https://doi.org/10.1186/s43166-021-00107-9

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