HTRA1 from OVX rat osteoclasts causes detrimental effects on endplate chondrocytes through NF-κB

HTRA1 from OVX rat osteoclasts causes detrimental effects on endplate chondrocytes through NF-κB

Endplate osteochondritis is considered one of the major causes of intervertebral disc degeneration (IVDD) and low back pain. Menopausal women have a higher rate of endplate cartilage degeneration than similarly aged men, but the related mechanisms are still unclear. Subchondral bone changes, mainly...

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Bibliographic Details
Main Authors: Longting Chen, Yiming Zhong, Shang Sun, Zihuan Yang, Haofeng Hong, Da Zou, Chunli Song, Weishi Li, Huijie Leng
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
Osteoclast
Endplate cartilage
Estrogen deficiency
HTRA1
NF-κB
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402304803X

Internet

http://www.sciencedirect.com/science/article/pii/S240584402304803X

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