Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration

Abstract Our previous work demonstrated the tendon-derived extracellular matrix (ECM) extracts as vital niches to specifically direct mesenchymal stem cells towards tenogenic differentiation. This study aims to further define the effective ECM molecules capable of teno-lineage induction on human adi...

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Bibliographic Details
Main Authors: Tian Tu, Yuan Shi, Boya Zhou, Xiaoyu Wang, Wenjie Zhang, Guangdong Zhou, Xiumei Mo, Wenbo Wang, Jinglei Wu, Wei Liu
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-023-00341-z