ASXL gain-of-function truncation mutants: defective and dysregulated forms of a natural ribosomal frameshifting product?

ASXL gain-of-function truncation mutants: defective and dysregulated forms of a natural ribosomal frameshifting product?

Abstract Background Programmed ribosomal frameshifting (PRF) is a gene expression mechanism which enables the translation of two N-terminally coincident, C-terminally distinct protein products from a single mRNA. Many viruses utilize PRF to control or regulate gene expression, but very few phylogene...

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Bibliographic Details
Main Authors: Adam M. Dinan, John F. Atkins, Andrew E. Firth
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Biology Direct
Subjects:
Ribosomal frameshifting
Translation
Protein synthesis
ASXL1
ASXL2
HCF-1
Online Access:http://link.springer.com/article/10.1186/s13062-017-0195-0

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http://link.springer.com/article/10.1186/s13062-017-0195-0

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