Synthesis, In Silico and In Vitro Characterization of Novel <i>N</i>,<i>N</i>-Substituted Pyrazolopyrimidine Acetamide Derivatives for the 18KDa Translocator Protein (TSPO)

Synthesis, In Silico and In Vitro Characterization of Novel <i>N</i>,<i>N</i>-Substituted Pyrazolopyrimidine Acetamide Derivatives for the 18KDa Translocator Protein (TSPO)

The translocator protein (TSPO) is an interesting biological target for molecular imaging and therapy because the overexpression of TSPO is associated with microglial activation caused by neuronal damage or neuroinflammation, and these activated microglia are involved in various central nervous syst...

書誌詳細
主要な著者:	Jaekyung Park, Sobia Wasim, Jae Ho Jung, Mi-hyun Kim, Byung Chul Lee, Mohammad Maqusood Alam, Sang-Yoon Lee
フォーマット:	論文
言語:	English
出版事項:	MDPI AG 2023-04-01
シリーズ:	Pharmaceuticals
主題:	translocator protein (TSPO) microglia neuroinflammation neurodegenerative disease central nervous system (CNS) pyrazolopyrimidine
オンライン･アクセス:	https://www.mdpi.com/1424-8247/16/4/576

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