Synthesis, In Silico and In Vitro Characterization of Novel <i>N</i>,<i>N</i>-Substituted Pyrazolopyrimidine Acetamide Derivatives for the 18KDa Translocator Protein (TSPO)

The translocator protein (TSPO) is an interesting biological target for molecular imaging and therapy because the overexpression of TSPO is associated with microglial activation caused by neuronal damage or neuroinflammation, and these activated microglia are involved in various central nervous syst...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Jaekyung Park, Sobia Wasim, Jae Ho Jung, Mi-hyun Kim, Byung Chul Lee, Mohammad Maqusood Alam, Sang-Yoon Lee
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2023-04-01
Цуврал:Pharmaceuticals
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/1424-8247/16/4/576

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