lncRNA Profiling of Exosomes and Its Communication Role in Regulating Silica-Stimulated Macrophage Apoptosis and Fibroblast Activation

lncRNA Profiling of Exosomes and Its Communication Role in Regulating Silica-Stimulated Macrophage Apoptosis and Fibroblast Activation

Long-term silica particle exposure leads to interstitial pulmonary inflammation and fibrosis, called silicosis. Silica-activated macrophages secrete a wide range of cytokines resulting in persistent inflammation. In addition, silica-stimulated activation of fibroblast is another checkpoint in the pr...

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Bibliographic Details
Main Authors: Jiaqi Ban, Shuai Chang, Pengwei Ma, Xin Wang, Fangwei Liu
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomolecules
Subjects:
exosomes
long non-coding RNA
cell communication
silicosis
macrophages
fibroblasts
Online Access:https://www.mdpi.com/2218-273X/14/2/146

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