Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data

Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data

Abstract Long non-coding RNA (lncRNA) regulates many physiological processes by acting as competitive endogenous RNA (ceRNA). The dysregulation of lncRNA X-inactive specific transcript (XIST) has been shown in various human disorders. However, its role in the pathogenesis of polycystic ovary syndrom...

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Bibliographic Details
Main Authors: Elahe Berenji, Ali Valipour Motlagh, Marziyeh Fathi, Maryam Esmaeili, Tayebeh Izadi, Parsa Rezvanian, Maryam Zanjirband, Zahra Safaeinejad, Mohammad Hossein Nasr-Esfahani
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Polycystic ovary syndrome
XIST
ceRNA network
Biomarker
Drug repositioning
Online Access:https://doi.org/10.1038/s41598-024-56524-1

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