Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin
Pyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of <i>Pseudomonas aeruginosa.</i> From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therap...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/4/927 |
_version_ | 1797412002887368704 |
---|---|
author | Thiago Gonçalves Ulrich Vasconcelos |
author_facet | Thiago Gonçalves Ulrich Vasconcelos |
author_sort | Thiago Gonçalves |
collection | DOAJ |
description | Pyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of <i>Pseudomonas aeruginosa.</i> From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therapy, even before the discovery of penicillin opened the era of antibiotic therapy, as well as its use in electric current generation. Exhibiting an exuberant blue colour and being easy to obtain, this pigment is the subject of the present review, aiming to narrate its history as well as to unveil its mechanisms and suggest new horizons for applications in different areas of engineering, biology and biotechnology. |
first_indexed | 2024-03-09T04:54:43Z |
format | Article |
id | doaj.art-febf2ea13f7146c18aaec89e1cf34454 |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-03-09T04:54:43Z |
publishDate | 2021-02-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-febf2ea13f7146c18aaec89e1cf344542023-12-03T13:07:43ZengMDPI AGMolecules1420-30492021-02-0126492710.3390/molecules26040927Colour Me Blue: The History and the Biotechnological Potential of PyocyaninThiago Gonçalves0Ulrich Vasconcelos1Centro de Biotecnologia, Departamento de Biotecnologia, Universidade Federal da Paraíba, R. Ipê Amarelo, s/n, Campus I, João Pessoa PB-CEP 58051-900, BrazilCentro de Biotecnologia, Departamento de Biotecnologia, Universidade Federal da Paraíba, R. Ipê Amarelo, s/n, Campus I, João Pessoa PB-CEP 58051-900, BrazilPyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of <i>Pseudomonas aeruginosa.</i> From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therapy, even before the discovery of penicillin opened the era of antibiotic therapy, as well as its use in electric current generation. Exhibiting an exuberant blue colour and being easy to obtain, this pigment is the subject of the present review, aiming to narrate its history as well as to unveil its mechanisms and suggest new horizons for applications in different areas of engineering, biology and biotechnology.https://www.mdpi.com/1420-3049/26/4/927bacterial pigments<i>Pseudomonas aeruginosa</i>pyocyanasebioprospecting |
spellingShingle | Thiago Gonçalves Ulrich Vasconcelos Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin Molecules bacterial pigments <i>Pseudomonas aeruginosa</i> pyocyanase bioprospecting |
title | Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin |
title_full | Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin |
title_fullStr | Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin |
title_full_unstemmed | Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin |
title_short | Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin |
title_sort | colour me blue the history and the biotechnological potential of pyocyanin |
topic | bacterial pigments <i>Pseudomonas aeruginosa</i> pyocyanase bioprospecting |
url | https://www.mdpi.com/1420-3049/26/4/927 |
work_keys_str_mv | AT thiagogoncalves colourmebluethehistoryandthebiotechnologicalpotentialofpyocyanin AT ulrichvasconcelos colourmebluethehistoryandthebiotechnologicalpotentialofpyocyanin |