Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin

Pyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of <i>Pseudomonas aeruginosa.</i> From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therap...

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Main Authors: Thiago Gonçalves, Ulrich Vasconcelos
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/4/927
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author Thiago Gonçalves
Ulrich Vasconcelos
author_facet Thiago Gonçalves
Ulrich Vasconcelos
author_sort Thiago Gonçalves
collection DOAJ
description Pyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of <i>Pseudomonas aeruginosa.</i> From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therapy, even before the discovery of penicillin opened the era of antibiotic therapy, as well as its use in electric current generation. Exhibiting an exuberant blue colour and being easy to obtain, this pigment is the subject of the present review, aiming to narrate its history as well as to unveil its mechanisms and suggest new horizons for applications in different areas of engineering, biology and biotechnology.
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spelling doaj.art-febf2ea13f7146c18aaec89e1cf344542023-12-03T13:07:43ZengMDPI AGMolecules1420-30492021-02-0126492710.3390/molecules26040927Colour Me Blue: The History and the Biotechnological Potential of PyocyaninThiago Gonçalves0Ulrich Vasconcelos1Centro de Biotecnologia, Departamento de Biotecnologia, Universidade Federal da Paraíba, R. Ipê Amarelo, s/n, Campus I, João Pessoa PB-CEP 58051-900, BrazilCentro de Biotecnologia, Departamento de Biotecnologia, Universidade Federal da Paraíba, R. Ipê Amarelo, s/n, Campus I, João Pessoa PB-CEP 58051-900, BrazilPyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of <i>Pseudomonas aeruginosa.</i> From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therapy, even before the discovery of penicillin opened the era of antibiotic therapy, as well as its use in electric current generation. Exhibiting an exuberant blue colour and being easy to obtain, this pigment is the subject of the present review, aiming to narrate its history as well as to unveil its mechanisms and suggest new horizons for applications in different areas of engineering, biology and biotechnology.https://www.mdpi.com/1420-3049/26/4/927bacterial pigments<i>Pseudomonas aeruginosa</i>pyocyanasebioprospecting
spellingShingle Thiago Gonçalves
Ulrich Vasconcelos
Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin
Molecules
bacterial pigments
<i>Pseudomonas aeruginosa</i>
pyocyanase
bioprospecting
title Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin
title_full Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin
title_fullStr Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin
title_full_unstemmed Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin
title_short Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin
title_sort colour me blue the history and the biotechnological potential of pyocyanin
topic bacterial pigments
<i>Pseudomonas aeruginosa</i>
pyocyanase
bioprospecting
url https://www.mdpi.com/1420-3049/26/4/927
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