Differentiation of glioblastoma tissues using spontaneous Raman scattering with dimensionality reduction and data classification

Differentiation of glioblastoma tissues using spontaneous Raman scattering with dimensionality reduction and data classification

The neurosurgery of intracranial tumors is often complicated by the difficulty of distinguishing tumor center, infiltration area, and normal tissue. The current standard for intraoperative navigation is fluorescent diagnostics with a fluorescent agent. This approach can be further enhanced by measur...

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Bibliographic Details
Main Authors: Igor Romanishkin, Tatiana Savelieva, Alexandra Kosyrkova, Vladimir Okhlopkov, Svetlana Shugai, Arseniy Orlov, Alexander Kravchuk, Sergey Goryaynov, Denis Golbin, Galina Pavlova, Igor Pronin, Victor Loschenov
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
glioblastoma multiforme
raman spectroscopy
dimensionality reduction
principal component analysis
biochemical components
optical biopsy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.944210/full

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