Study of histopathological patterns of endometrium in abnormal uterine bleeding
Background: Abnormal uterine bleeding (AUB) is a common gynecological complaint associated with considerable morbidity and significantly affects the patient′s family, personal and social life. The aim of the study was to analyze the histomorphological patterns of endometrium in patients presenting w...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | CHRISMED Journal of Health and Research |
| Subjects: | |
| Online Access: | http://www.cjhr.org/article.asp?issn=2348-3334;year=2014;volume=1;issue=2;spage=76;epage=81;aulast=Sajitha |
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| author | K Sajitha Shetty K Padma K Jayaprakash Shetty H L KishanPrasad Harish S Permi Panna Hegde |
| author_facet | K Sajitha Shetty K Padma K Jayaprakash Shetty H L KishanPrasad Harish S Permi Panna Hegde |
| author_sort | K Sajitha |
| collection | DOAJ |
| description | Background: Abnormal uterine bleeding (AUB) is a common gynecological complaint associated with considerable morbidity and significantly affects the patient′s family, personal and social life. The aim of the study was to analyze the histomorphological patterns of endometrium in patients presenting with AUB and also to determine the incidence of AUB in various age groups. Materials and Methods: This is a prospective study, conducted in the Department of Pathology, in a tertiary care teaching hospital, Mangalore from October 2011 till date. All cases of AUB with a probable endometrial cause were included in the study. Data was entered in Microsoft Excel and managed in Statistical Package for the Social Sciences (SPSS) version 16. Analysis was done in the form of percentages and proportions and represented as tables where necessary. Results: A total of 156 cases were analyzed. Patients′ age ranged from 23-78 years. AUB was most prevalent in the perimenopausal age group. The most common presenting complaint was menorrhagia (47%). Endometrial hyperplasia was the most common histopathological finding and was seen in 25% patients, followed by secretory endometrium in 16.7% patients, and proliferative phase pattern and disordered proliferative endometrium were seen in 12.2% patients each. Malignancy was detected in 6.4% of cases and endometrial carcinoma was the most common lesion (4.5%). Conclusions: Histopathological evaluation of endometrial samples is especially indicated in women over the age of 35 years to rule out malignancy and preneoplasia. Among the patients with no organic pathology, normal physiological patterns with proliferative, secretory, and menstrual changes were observed. The most common endometrial pathology in this series was endometrial hyperplasia. |
| first_indexed | 2024-12-21T11:48:20Z |
| format | Article |
| id | doaj.art-fec1f31d1326481aa9ec13cc9b931750 |
| institution | Directory Open Access Journal |
| issn | 2348-3334 2348-506X |
| language | English |
| last_indexed | 2024-12-21T11:48:20Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | CHRISMED Journal of Health and Research |
| spelling | doaj.art-fec1f31d1326481aa9ec13cc9b9317502022-12-21T19:05:08ZengWolters Kluwer Medknow PublicationsCHRISMED Journal of Health and Research2348-33342348-506X2014-01-0112768110.4103/2348-3334.134265Study of histopathological patterns of endometrium in abnormal uterine bleedingK SajithaShetty K PadmaK Jayaprakash ShettyH L KishanPrasadHarish S PermiPanna HegdeBackground: Abnormal uterine bleeding (AUB) is a common gynecological complaint associated with considerable morbidity and significantly affects the patient′s family, personal and social life. The aim of the study was to analyze the histomorphological patterns of endometrium in patients presenting with AUB and also to determine the incidence of AUB in various age groups. Materials and Methods: This is a prospective study, conducted in the Department of Pathology, in a tertiary care teaching hospital, Mangalore from October 2011 till date. All cases of AUB with a probable endometrial cause were included in the study. Data was entered in Microsoft Excel and managed in Statistical Package for the Social Sciences (SPSS) version 16. Analysis was done in the form of percentages and proportions and represented as tables where necessary. Results: A total of 156 cases were analyzed. Patients′ age ranged from 23-78 years. AUB was most prevalent in the perimenopausal age group. The most common presenting complaint was menorrhagia (47%). Endometrial hyperplasia was the most common histopathological finding and was seen in 25% patients, followed by secretory endometrium in 16.7% patients, and proliferative phase pattern and disordered proliferative endometrium were seen in 12.2% patients each. Malignancy was detected in 6.4% of cases and endometrial carcinoma was the most common lesion (4.5%). Conclusions: Histopathological evaluation of endometrial samples is especially indicated in women over the age of 35 years to rule out malignancy and preneoplasia. Among the patients with no organic pathology, normal physiological patterns with proliferative, secretory, and menstrual changes were observed. The most common endometrial pathology in this series was endometrial hyperplasia.http://www.cjhr.org/article.asp?issn=2348-3334;year=2014;volume=1;issue=2;spage=76;epage=81;aulast=SajithaAbnormal uterine bleedingdilatation and curettagedysfunctional uterine bleedingendometrium |
| spellingShingle | K Sajitha Shetty K Padma K Jayaprakash Shetty H L KishanPrasad Harish S Permi Panna Hegde Study of histopathological patterns of endometrium in abnormal uterine bleeding CHRISMED Journal of Health and Research Abnormal uterine bleeding dilatation and curettage dysfunctional uterine bleeding endometrium |
| title | Study of histopathological patterns of endometrium in abnormal uterine bleeding |
| title_full | Study of histopathological patterns of endometrium in abnormal uterine bleeding |
| title_fullStr | Study of histopathological patterns of endometrium in abnormal uterine bleeding |
| title_full_unstemmed | Study of histopathological patterns of endometrium in abnormal uterine bleeding |
| title_short | Study of histopathological patterns of endometrium in abnormal uterine bleeding |
| title_sort | study of histopathological patterns of endometrium in abnormal uterine bleeding |
| topic | Abnormal uterine bleeding dilatation and curettage dysfunctional uterine bleeding endometrium |
| url | http://www.cjhr.org/article.asp?issn=2348-3334;year=2014;volume=1;issue=2;spage=76;epage=81;aulast=Sajitha |
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