A quality‐of‐life questionnaire for heavy menstrual bleeding in Thai women receiving oral antithrombotics: Assessment of the translated Menstrual Bleeding Questionnaire
Abstract Background Heavy menstrual bleeding (HMB) is common among reproductive‐aged women receiving oral antithrombotics and frequently results in a negative impact on quality of life. Methods We translated the Menstrual Bleeding Questionnaire (MBQ) into Thai by forward translation, back‐translatio...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-10-01
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| Series: | Research and Practice in Thrombosis and Haemostasis |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rth2.12617 |
| _version_ | 1827848548649009152 |
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| author | Tinaram Rodpetch Jittima Manonai Pantep Angchaisuksiri Kochawan Boonyawat |
| author_facet | Tinaram Rodpetch Jittima Manonai Pantep Angchaisuksiri Kochawan Boonyawat |
| author_sort | Tinaram Rodpetch |
| collection | DOAJ |
| description | Abstract Background Heavy menstrual bleeding (HMB) is common among reproductive‐aged women receiving oral antithrombotics and frequently results in a negative impact on quality of life. Methods We translated the Menstrual Bleeding Questionnaire (MBQ) into Thai by forward translation, back‐translation, pretesting, and cognitive interviewing. The translated questionnaire was content validated by a gynecologist. A validation study was conducted for the translated MBQ and defined the optimal score for the diagnosis of HMB. We then performed a cross‐sectional study to determine the prevalence of HMB using the translated MBQ. Reproductive‐aged Thai women who visited outpatient clinics receiving oral antithrombotics were asked to assess menstrual characteristics after receiving antithrombotics. The impact of menstruation on quality of life was assessed by using the MBQ. Results The translated MBQ had excellent reliability (intraclass correlation coefficient = 0.93) and discriminated between women with and without HMB (area under the receiver operating characteristic curve = 0.93). A score of 21.5 had 82.9% sensitivity and 83.1% specificity in the diagnosis of HMB. The mean (standard deviation) of the score was significantly higher in the HMB group than in the normal menstrual bleeding group (30.4 [9.4] vs 15.4 [5.6]; P < .001, respectively). Of the 49 women, the prevalence of HMB in patients receiving warfarin (n = 29), direct oral anticoagulants (n = 4), or antiplatelet agents (n = 16) was 27.6%, 25.0%, and 25.0%, respectively. Conclusions MBQ is a simple and valid tool that can be applied to screen women experiencing HMB. One‐fourth of reproductive‐aged women who received oral antithrombotics experienced HMB that impacted their quality of life. |
| first_indexed | 2024-03-12T09:48:41Z |
| format | Article |
| id | doaj.art-fec598f65fd647d88a7cea56326163dd |
| institution | Directory Open Access Journal |
| issn | 2475-0379 |
| language | English |
| last_indexed | 2024-03-12T09:48:41Z |
| publishDate | 2021-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Research and Practice in Thrombosis and Haemostasis |
| spelling | doaj.art-fec598f65fd647d88a7cea56326163dd2023-09-02T12:45:05ZengElsevierResearch and Practice in Thrombosis and Haemostasis2475-03792021-10-0157n/an/a10.1002/rth2.12617A quality‐of‐life questionnaire for heavy menstrual bleeding in Thai women receiving oral antithrombotics: Assessment of the translated Menstrual Bleeding QuestionnaireTinaram Rodpetch0Jittima Manonai1Pantep Angchaisuksiri2Kochawan Boonyawat3Department of Medicine Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok ThailandDepartment of Obstetrics and Gynecology Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok ThailandDepartment of Medicine Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok ThailandDepartment of Medicine Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok ThailandAbstract Background Heavy menstrual bleeding (HMB) is common among reproductive‐aged women receiving oral antithrombotics and frequently results in a negative impact on quality of life. Methods We translated the Menstrual Bleeding Questionnaire (MBQ) into Thai by forward translation, back‐translation, pretesting, and cognitive interviewing. The translated questionnaire was content validated by a gynecologist. A validation study was conducted for the translated MBQ and defined the optimal score for the diagnosis of HMB. We then performed a cross‐sectional study to determine the prevalence of HMB using the translated MBQ. Reproductive‐aged Thai women who visited outpatient clinics receiving oral antithrombotics were asked to assess menstrual characteristics after receiving antithrombotics. The impact of menstruation on quality of life was assessed by using the MBQ. Results The translated MBQ had excellent reliability (intraclass correlation coefficient = 0.93) and discriminated between women with and without HMB (area under the receiver operating characteristic curve = 0.93). A score of 21.5 had 82.9% sensitivity and 83.1% specificity in the diagnosis of HMB. The mean (standard deviation) of the score was significantly higher in the HMB group than in the normal menstrual bleeding group (30.4 [9.4] vs 15.4 [5.6]; P < .001, respectively). Of the 49 women, the prevalence of HMB in patients receiving warfarin (n = 29), direct oral anticoagulants (n = 4), or antiplatelet agents (n = 16) was 27.6%, 25.0%, and 25.0%, respectively. Conclusions MBQ is a simple and valid tool that can be applied to screen women experiencing HMB. One‐fourth of reproductive‐aged women who received oral antithrombotics experienced HMB that impacted their quality of life.https://doi.org/10.1002/rth2.12617anticoagulantsantiplatelet drugsheavy menstrual bleedingquality of lifequestionnaires |
| spellingShingle | Tinaram Rodpetch Jittima Manonai Pantep Angchaisuksiri Kochawan Boonyawat A quality‐of‐life questionnaire for heavy menstrual bleeding in Thai women receiving oral antithrombotics: Assessment of the translated Menstrual Bleeding Questionnaire Research and Practice in Thrombosis and Haemostasis anticoagulants antiplatelet drugs heavy menstrual bleeding quality of life questionnaires |
| title | A quality‐of‐life questionnaire for heavy menstrual bleeding in Thai women receiving oral antithrombotics: Assessment of the translated Menstrual Bleeding Questionnaire |
| title_full | A quality‐of‐life questionnaire for heavy menstrual bleeding in Thai women receiving oral antithrombotics: Assessment of the translated Menstrual Bleeding Questionnaire |
| title_fullStr | A quality‐of‐life questionnaire for heavy menstrual bleeding in Thai women receiving oral antithrombotics: Assessment of the translated Menstrual Bleeding Questionnaire |
| title_full_unstemmed | A quality‐of‐life questionnaire for heavy menstrual bleeding in Thai women receiving oral antithrombotics: Assessment of the translated Menstrual Bleeding Questionnaire |
| title_short | A quality‐of‐life questionnaire for heavy menstrual bleeding in Thai women receiving oral antithrombotics: Assessment of the translated Menstrual Bleeding Questionnaire |
| title_sort | quality of life questionnaire for heavy menstrual bleeding in thai women receiving oral antithrombotics assessment of the translated menstrual bleeding questionnaire |
| topic | anticoagulants antiplatelet drugs heavy menstrual bleeding quality of life questionnaires |
| url | https://doi.org/10.1002/rth2.12617 |
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