Cytotoxicity against HL60 Cells of Ficifolidione Derivatives with Methyl, <i>n</i>-Pentyl, and <i>n</i>-Heptyl Groups

Cytotoxicity against HL60 Cells of Ficifolidione Derivatives with Methyl, <i>n</i>-Pentyl, and <i>n</i>-Heptyl Groups

Ficifolidione, a natural insecticidal compound isolated from the essential oils of Myetaceae species, is a spiro phloroglucinol with an isobutyl group at the C-4 position. We found that ficifolidione showed cytotoxicity against cancer cells via apoptosis. Replacement of the isobutyl group by <i&g...

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Bibliographic Details
Main Authors: Hisashi Nishiwaki, Megumi Ikari, Satomi Fujiwara, Kosuke Nishi, Takuya Sugahara, Koichi Akiyama, Satoshi Yamauchi
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Molecules
Subjects:
phloroglucinol
ficifolidione
hl60
cytotoxicity
Online Access:https://www.mdpi.com/1420-3049/24/22/4081

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