Relationship between Circadian Phase Delay without Morning Light and Phase Advance by Bright Light Exposure the Following Morning

Humans have a circadian rhythm for which the period varies among individuals. In the present study, we investigated the amount of natural phase delay of circadian rhythms after spending a day under dim light (Day 1 to Day 2) and the amount of phase advance due to light exposure (8000 lx, 4100 K) the...

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Bibliographic Details
Main Authors: Michihiro Ohashi, Taisuke Eto, Toaki Takasu, Yuki Motomura, Shigekazu Higuchi
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Clocks & Sleep
Subjects:
Online Access:https://www.mdpi.com/2624-5175/5/4/41
Description
Summary:Humans have a circadian rhythm for which the period varies among individuals. In the present study, we investigated the amount of natural phase delay of circadian rhythms after spending a day under dim light (Day 1 to Day 2) and the amount of phase advance due to light exposure (8000 lx, 4100 K) the following morning (Day 2 to Day 3). The relationships of the phase shifts with the circadian phase, chronotype and sleep habits were also investigated. Dim light melatonin onset (DLMO) was investigated as a circadian phase marker on each day. In the 27 individuals used for the analysis, DLMO was delayed significantly (−0.24 ± 0.33 h, <i>p</i> < 0.01) from Day 1 to Day 2 and DLMO was advanced significantly (0.18 ± 0.36 h, <i>p</i> < 0.05) from Day 2 to Day 3. There was a significant correlation between phase shifts, with subjects who had a greater phase delay in the dim environment having a greater phase advance by light exposure (r = −0.43, <i>p</i> < 0.05). However, no significant correlations with circadian phase, chronotype or sleep habits were found. These phase shifts may reflect the stability of the phase, but do not account for an individual’s chronotype-related indicators.
ISSN:2624-5175