A Low-Phenylalanine-Containing Whey Protein Hydrolysate Stimulates Osteogenic Activity through the Activation of p38/Runx2 Signaling in Osteoblast Cells

A Low-Phenylalanine-Containing Whey Protein Hydrolysate Stimulates Osteogenic Activity through the Activation of p38/Runx2 Signaling in Osteoblast Cells

A phenylalanine (Phe)-restricted diet is indispensable for individuals suffering from phenylketonuria (PKU). Our previous study reported a low-Phe-containing whey protein hydrolysate (LPH) prepared from a selected whey protein hydrolysate (TA2H). This study aimed to investigate the osteogenic activi...

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Bibliographic Details
Main Authors: Tingting Bu, Yuting Ren, Songfeng Yu, Jiexia Zheng, Ling Liu, Peilong Sun, Jianping Wu, Kai Yang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Nutrients
Subjects:
phenylketonuria
whey protein hydrolysate
osteoblasts
differentiation
runt-related transcription factor 2
p38 mitogen-activated protein kinase
Online Access:https://www.mdpi.com/2072-6643/14/15/3135

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https://www.mdpi.com/2072-6643/14/15/3135

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