Leg ulcers in sickle cell patients: management challenges
Arij M El Khatib,1 Shady N Hayek2 1Division of Plastic and Reconstructive Surgery, Department of Surgery, American University of Beirut Medical Center (AUBMC), 2Private Practice, Cosmetic Surgery Center, Beirut, Lebanon Abstract: Sickle cell disease is an autosomal recessive hemoglobinopathy caused...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2016-11-01
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| Series: | Chronic Wound Care Management and Research |
| Subjects: | |
| Online Access: | https://www.dovepress.com/leg-ulcers-in-sickle-cell-patients-management-challenges-peer-reviewed-article-CWCMR |
| _version_ | 1819084833949745152 |
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| author | El Khatib AM Hayek SN |
| author_facet | El Khatib AM Hayek SN |
| author_sort | El Khatib AM |
| collection | DOAJ |
| description | Arij M El Khatib,1 Shady N Hayek2 1Division of Plastic and Reconstructive Surgery, Department of Surgery, American University of Beirut Medical Center (AUBMC), 2Private Practice, Cosmetic Surgery Center, Beirut, Lebanon Abstract: Sickle cell disease is an autosomal recessive hemoglobinopathy caused by an amino acid substitution from glutamic acid to valine in the beta hemoglobin chain. One of the common symptoms occurring in sickle cell patients are leg ulcers, which are notoriously painful, difficult to treat, and frequently recurrent. These ulcers pose a therapeutic challenge with multiple modalities proposed for treatment, but with scarce evidence of efficacy of any single modality. Ulcer prevention, rigorous wound care, pain control, and surgery are the current mainstays of sickle cell leg ulcer treatment. Keywords: sickle cell leg ulcer, leg wound, sickle cell disease |
| first_indexed | 2024-12-21T20:54:45Z |
| format | Article |
| id | doaj.art-fed2bf41fbb4434992b7918e4bbfa7e0 |
| institution | Directory Open Access Journal |
| issn | 2324-481X |
| language | English |
| last_indexed | 2024-12-21T20:54:45Z |
| publishDate | 2016-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Chronic Wound Care Management and Research |
| spelling | doaj.art-fed2bf41fbb4434992b7918e4bbfa7e02022-12-21T18:50:38ZengDove Medical PressChronic Wound Care Management and Research2324-481X2016-11-01Volume 315716130038Leg ulcers in sickle cell patients: management challengesEl Khatib AMHayek SNArij M El Khatib,1 Shady N Hayek2 1Division of Plastic and Reconstructive Surgery, Department of Surgery, American University of Beirut Medical Center (AUBMC), 2Private Practice, Cosmetic Surgery Center, Beirut, Lebanon Abstract: Sickle cell disease is an autosomal recessive hemoglobinopathy caused by an amino acid substitution from glutamic acid to valine in the beta hemoglobin chain. One of the common symptoms occurring in sickle cell patients are leg ulcers, which are notoriously painful, difficult to treat, and frequently recurrent. These ulcers pose a therapeutic challenge with multiple modalities proposed for treatment, but with scarce evidence of efficacy of any single modality. Ulcer prevention, rigorous wound care, pain control, and surgery are the current mainstays of sickle cell leg ulcer treatment. Keywords: sickle cell leg ulcer, leg wound, sickle cell disease https://www.dovepress.com/leg-ulcers-in-sickle-cell-patients-management-challenges-peer-reviewed-article-CWCMRSickle cell leg ulcerleg woundsickle cell disease |
| spellingShingle | El Khatib AM Hayek SN Leg ulcers in sickle cell patients: management challenges Chronic Wound Care Management and Research Sickle cell leg ulcer leg wound sickle cell disease |
| title | Leg ulcers in sickle cell patients: management challenges |
| title_full | Leg ulcers in sickle cell patients: management challenges |
| title_fullStr | Leg ulcers in sickle cell patients: management challenges |
| title_full_unstemmed | Leg ulcers in sickle cell patients: management challenges |
| title_short | Leg ulcers in sickle cell patients: management challenges |
| title_sort | leg ulcers in sickle cell patients management challenges |
| topic | Sickle cell leg ulcer leg wound sickle cell disease |
| url | https://www.dovepress.com/leg-ulcers-in-sickle-cell-patients-management-challenges-peer-reviewed-article-CWCMR |
| work_keys_str_mv | AT elkhatibam legulcersinsicklecellpatientsmanagementchallenges AT hayeksn legulcersinsicklecellpatientsmanagementchallenges |