Electrophoretic Deposition of Biocompatible and Bioactive Hydroxyapatite-Based Coatings on Titanium
Current trends in biomaterials science address the issue of integrating artificial materials as orthopedic or dental implants with biological materials, e.g., patients’ bone tissue. Problems arise due to the simple fact that any surface that promotes biointegration and facilitates osteointegration m...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/14/18/5391 |
| _version_ | 1797518415037988864 |
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| author | Marija Djošić Ana Janković Vesna Mišković-Stanković |
| author_facet | Marija Djošić Ana Janković Vesna Mišković-Stanković |
| author_sort | Marija Djošić |
| collection | DOAJ |
| description | Current trends in biomaterials science address the issue of integrating artificial materials as orthopedic or dental implants with biological materials, e.g., patients’ bone tissue. Problems arise due to the simple fact that any surface that promotes biointegration and facilitates osteointegration may also provide a good platform for the rapid growth of bacterial colonies. Infected implant surfaces easily lead to biofilm formation that poses a major healthcare concern since it could have destructive effects and ultimately endanger the patients’ life. As of late, research has centered on designing coatings that would eliminate possible infection but neglected to aid bone mineralization. Other strategies yielded surfaces that could promote osseointegration but failed to prevent microbial susceptibility. Needless to say, in order to assure prolonged implant functionality, both coating functions are indispensable and should be addressed simultaneously. This review summarizes progress in designing multifunctional implant coatings that serve as carriers of antibacterial agents with the primary intention of inhibiting bacterial growth on the implant-tissue interface, while still promoting osseointegration. |
| first_indexed | 2024-03-10T07:29:33Z |
| format | Article |
| id | doaj.art-fed4bf34ef8f4389938b760debca941b |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T07:29:33Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-fed4bf34ef8f4389938b760debca941b2023-11-22T14:03:19ZengMDPI AGMaterials1996-19442021-09-011418539110.3390/ma14185391Electrophoretic Deposition of Biocompatible and Bioactive Hydroxyapatite-Based Coatings on TitaniumMarija Djošić0Ana Janković1Vesna Mišković-Stanković2Institute for Technology of Nuclear and Other Mineral Raw Materials, Bulevar Franš d’Eperea 86, 11000 Belgrade, SerbiaFaculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11000 Belgrade, SerbiaFaculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11000 Belgrade, SerbiaCurrent trends in biomaterials science address the issue of integrating artificial materials as orthopedic or dental implants with biological materials, e.g., patients’ bone tissue. Problems arise due to the simple fact that any surface that promotes biointegration and facilitates osteointegration may also provide a good platform for the rapid growth of bacterial colonies. Infected implant surfaces easily lead to biofilm formation that poses a major healthcare concern since it could have destructive effects and ultimately endanger the patients’ life. As of late, research has centered on designing coatings that would eliminate possible infection but neglected to aid bone mineralization. Other strategies yielded surfaces that could promote osseointegration but failed to prevent microbial susceptibility. Needless to say, in order to assure prolonged implant functionality, both coating functions are indispensable and should be addressed simultaneously. This review summarizes progress in designing multifunctional implant coatings that serve as carriers of antibacterial agents with the primary intention of inhibiting bacterial growth on the implant-tissue interface, while still promoting osseointegration.https://www.mdpi.com/1996-1944/14/18/5391antibacterial coatinghydroxyapatitesilvergentamicinelectrophoretic depositionimplants |
| spellingShingle | Marija Djošić Ana Janković Vesna Mišković-Stanković Electrophoretic Deposition of Biocompatible and Bioactive Hydroxyapatite-Based Coatings on Titanium Materials antibacterial coating hydroxyapatite silver gentamicin electrophoretic deposition implants |
| title | Electrophoretic Deposition of Biocompatible and Bioactive Hydroxyapatite-Based Coatings on Titanium |
| title_full | Electrophoretic Deposition of Biocompatible and Bioactive Hydroxyapatite-Based Coatings on Titanium |
| title_fullStr | Electrophoretic Deposition of Biocompatible and Bioactive Hydroxyapatite-Based Coatings on Titanium |
| title_full_unstemmed | Electrophoretic Deposition of Biocompatible and Bioactive Hydroxyapatite-Based Coatings on Titanium |
| title_short | Electrophoretic Deposition of Biocompatible and Bioactive Hydroxyapatite-Based Coatings on Titanium |
| title_sort | electrophoretic deposition of biocompatible and bioactive hydroxyapatite based coatings on titanium |
| topic | antibacterial coating hydroxyapatite silver gentamicin electrophoretic deposition implants |
| url | https://www.mdpi.com/1996-1944/14/18/5391 |
| work_keys_str_mv | AT marijadjosic electrophoreticdepositionofbiocompatibleandbioactivehydroxyapatitebasedcoatingsontitanium AT anajankovic electrophoreticdepositionofbiocompatibleandbioactivehydroxyapatitebasedcoatingsontitanium AT vesnamiskovicstankovic electrophoreticdepositionofbiocompatibleandbioactivehydroxyapatitebasedcoatingsontitanium |