Influence of progesterone on GAD65 and GAD67 mRNA expression in the dorsolateral striatum and prefrontal cortex of female rats repeatedly treated with cocaine

Female rats are intensely affected by cocaine, with estrogen probably playing an important role in this effect. Progesterone modulates the GABA system and attenuates the effects of cocaine; however, there is no information about its relevance in changing GABA synthesis pathways after cocaine adminis...

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Bibliographic Details
Main Authors: M.F. Souza, V.M. Toniazo, A.P.G. Frazzon, H.M.T. Barros
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001100011