A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China
Currently, mushroom poisoning still poses a huge problem to humans' health and life globally. Poisoning incidents caused by Inosperma spp. were reported continuously in tropical China in recent years. In this study, a new poisonous Inosperma species, discovered from a poisoning incident, was de...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.923435/full |
| _version_ | 1811319075711746048 |
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| author | Lun-Sha Deng Wen-Jie Yu Nian-Kai Zeng Yi-Zhe Zhang Xiao-Peng Wu Hai-Jiao Li Fei Xu Yu-Guang Fan |
| author_facet | Lun-Sha Deng Wen-Jie Yu Nian-Kai Zeng Yi-Zhe Zhang Xiao-Peng Wu Hai-Jiao Li Fei Xu Yu-Guang Fan |
| author_sort | Lun-Sha Deng |
| collection | DOAJ |
| description | Currently, mushroom poisoning still poses a huge problem to humans' health and life globally. Poisoning incidents caused by Inosperma spp. were reported continuously in tropical China in recent years. In this study, a new poisonous Inosperma species, discovered from a poisoning incident, was described in tropical China based on morphological, molecular, and toxin detection evidence; detailed descriptions, photographs, and comparisons to closely related species were provided. For qualitative analysis, through targeted screening using ultra-high liquid chromatography triple quadrupole mass spectrometry (UPLC-MS/MS), the new species contains muscarine and no other toxins (two isoxazole derivatives, two tryptamine alkaloids, three amatoxins, and three phallotoxins). For quantitative analysis, muscarine contents in the pileus and the stipe were 2.08 ± 0.05 and 6.53 ± 1.88 g/kg, respectively. |
| first_indexed | 2024-04-13T12:35:56Z |
| format | Article |
| id | doaj.art-fed71111eccc4115bb2e033f9a20d819 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-13T12:35:56Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-fed71111eccc4115bb2e033f9a20d8192022-12-22T02:46:40ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-07-011310.3389/fmicb.2022.923435923435A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical ChinaLun-Sha Deng0Wen-Jie Yu1Nian-Kai Zeng2Yi-Zhe Zhang3Xiao-Peng Wu4Hai-Jiao Li5Fei Xu6Yu-Guang Fan7Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Key Laboratory for R&D of Tropical Herbs, Tropical Environment and Health Laboratory, School of Pharmacy & International School of Public Health and One Health, Hainan Medical University, Haikou, ChinaKey Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Key Laboratory for R&D of Tropical Herbs, Tropical Environment and Health Laboratory, School of Pharmacy & International School of Public Health and One Health, Hainan Medical University, Haikou, ChinaKey Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Key Laboratory for R&D of Tropical Herbs, Tropical Environment and Health Laboratory, School of Pharmacy & International School of Public Health and One Health, Hainan Medical University, Haikou, ChinaNational Institute of Occupational Health and Poison Control, Chinese Centre for Disease Control and Prevention, Beijing, ChinaAnalysis and Test Center, Chinese Academy of Tropical Agricultural Sciences, Haikou, ChinaNational Institute of Occupational Health and Poison Control, Chinese Centre for Disease Control and Prevention, Beijing, ChinaNingxia Key Laboratory of Environmental Factors and Chronic Diseases Control, School of Public Health and Management, Ningxia Medical University, Yinchuan, ChinaKey Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Key Laboratory for R&D of Tropical Herbs, Tropical Environment and Health Laboratory, School of Pharmacy & International School of Public Health and One Health, Hainan Medical University, Haikou, ChinaCurrently, mushroom poisoning still poses a huge problem to humans' health and life globally. Poisoning incidents caused by Inosperma spp. were reported continuously in tropical China in recent years. In this study, a new poisonous Inosperma species, discovered from a poisoning incident, was described in tropical China based on morphological, molecular, and toxin detection evidence; detailed descriptions, photographs, and comparisons to closely related species were provided. For qualitative analysis, through targeted screening using ultra-high liquid chromatography triple quadrupole mass spectrometry (UPLC-MS/MS), the new species contains muscarine and no other toxins (two isoxazole derivatives, two tryptamine alkaloids, three amatoxins, and three phallotoxins). For quantitative analysis, muscarine contents in the pileus and the stipe were 2.08 ± 0.05 and 6.53 ± 1.88 g/kg, respectively.https://www.frontiersin.org/articles/10.3389/fmicb.2022.923435/fullnew speciesmushroom poisoning incidentmuscarineultra-high liquid chromatography triple quadrupole mass spectrometrytropical China |
| spellingShingle | Lun-Sha Deng Wen-Jie Yu Nian-Kai Zeng Yi-Zhe Zhang Xiao-Peng Wu Hai-Jiao Li Fei Xu Yu-Guang Fan A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China Frontiers in Microbiology new species mushroom poisoning incident muscarine ultra-high liquid chromatography triple quadrupole mass spectrometry tropical China |
| title | A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China |
| title_full | A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China |
| title_fullStr | A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China |
| title_full_unstemmed | A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China |
| title_short | A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China |
| title_sort | new muscarine containing inosperma inocybaceae agaricales species discovered from one poisoning incident occurring in tropical china |
| topic | new species mushroom poisoning incident muscarine ultra-high liquid chromatography triple quadrupole mass spectrometry tropical China |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.923435/full |
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