Novel Anticancer NHC*-Gold(I) Complexes Inspired by Lepidiline A

Novel Anticancer NHC*-Gold(I) Complexes Inspired by Lepidiline A

<i>N</i>-Heterocyclic carbene gold(I) complexes derived from 1,3-dibenzyl-4,5-diphenylimidazol-2-ylidene (NHC*) represent a promising class of anticancer drugs. Complexes of the type NHC*-Au-L (L = Br<sup>−</sup>, I<sup>−</sup>, C≡C-R) and [NHC*-Au-L]<sup>+&...

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Bibliographic Details
Main Authors: Danielle Curran, Helge Müller-Bunz, Sofia I. Bär, Rainer Schobert, Xiangming Zhu, Matthias Tacke
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
gold
<i>N</i>-heterocyclic carbene
anticancer drug
aurophilic interactions
cytotoxicity
Lepidiline A
Online Access:https://www.mdpi.com/1420-3049/25/15/3474

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