Molecular Epidemiological Survey for Degenerative Myelopathy in German Shepherd Dogs in Japan: Allele Frequency and Clinical Progression Rate

Molecular Epidemiological Survey for Degenerative Myelopathy in German Shepherd Dogs in Japan: Allele Frequency and Clinical Progression Rate

Canine degenerative myelopathy (DM) is an adult-onset, chronic, progressive neurodegenerative disease reported in multiple canine breeds, including the German Shepherd Dog (GSD). Clinical signs include progressive motor neuron paralysis, which begins in the pelvic limbs and eventually leads to respi...

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Bibliographic Details
Main Authors: Shinichiro Maki, Md Shafiqul Islam, Tomohito Itoh, Masanobu Nurimoto, Akira Yabuki, Yu Furusawa, Hiroaki Kamishina, Yui Kobatake, Tofazzal Md Rakib, Martia Rani Tacharina, Osamu Yamato
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Animals
Subjects:
canine <i>SOD1</i> gene
degenerative myelopathy
dog breeding
German Shepherd Dog
mutant allele frequency
disease prevention
Online Access:https://www.mdpi.com/2076-2615/12/13/1647

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