Cost-effectiveness analysis of COVID-19 screening strategy under China's dynamic zero-case policy
This study aims to optimize the COVID-19 screening strategies under China's dynamic zero-case policy through cost-effectiveness analysis. A total of 9 screening strategies with different screening frequencies and combinations of detection methods were designed. A stochastic agent-based model wa...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1099116/full |
| _version_ | 1827951701471002624 |
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| author | Haonan Li Haonan Li Hui Zhang Hui Zhang |
| author_facet | Haonan Li Haonan Li Hui Zhang Hui Zhang |
| author_sort | Haonan Li |
| collection | DOAJ |
| description | This study aims to optimize the COVID-19 screening strategies under China's dynamic zero-case policy through cost-effectiveness analysis. A total of 9 screening strategies with different screening frequencies and combinations of detection methods were designed. A stochastic agent-based model was used to simulate the progress of the COVID-19 outbreak in scenario I (close contacts were promptly quarantined) and scenario II (close contacts were not promptly quarantined). The primary outcomes included the number of infections, number of close contacts, number of deaths, the duration of the epidemic, and duration of movement restriction. Net monetary benefit (NMB) and the incremental cost-benefit ratio were used to compare the cost-effectiveness of different screening strategies. The results indicated that under China's COVID-19 dynamic zero-case policy, high-frequency screening can help contain the spread of the epidemic, reduce the size and burden of the epidemic, and is cost-effective. Mass antigen testing is not cost-effective compared with mass nucleic acid testing in the same screening frequency. It would be more cost-effective to use AT as a supplemental screening tool when NAT capacity is insufficient or when outbreaks are spreading very rapidly. |
| first_indexed | 2024-04-09T13:46:32Z |
| format | Article |
| id | doaj.art-fee2aebfcc1b4ba8892a6c10aaba94bc |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-09T13:46:32Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-fee2aebfcc1b4ba8892a6c10aaba94bc2023-05-09T04:47:26ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-05-011110.3389/fpubh.2023.10991161099116Cost-effectiveness analysis of COVID-19 screening strategy under China's dynamic zero-case policyHaonan Li0Haonan Li1Hui Zhang2Hui Zhang3School of Medical Business, Guangdong Pharmaceutical University, Guangzhou, Guangdong, ChinaGuangdong Health Economics and Health Promotion Research Center, Guangzhou, Guangdong, ChinaSchool of Medical Business, Guangdong Pharmaceutical University, Guangzhou, Guangdong, ChinaGuangdong Health Economics and Health Promotion Research Center, Guangzhou, Guangdong, ChinaThis study aims to optimize the COVID-19 screening strategies under China's dynamic zero-case policy through cost-effectiveness analysis. A total of 9 screening strategies with different screening frequencies and combinations of detection methods were designed. A stochastic agent-based model was used to simulate the progress of the COVID-19 outbreak in scenario I (close contacts were promptly quarantined) and scenario II (close contacts were not promptly quarantined). The primary outcomes included the number of infections, number of close contacts, number of deaths, the duration of the epidemic, and duration of movement restriction. Net monetary benefit (NMB) and the incremental cost-benefit ratio were used to compare the cost-effectiveness of different screening strategies. The results indicated that under China's COVID-19 dynamic zero-case policy, high-frequency screening can help contain the spread of the epidemic, reduce the size and burden of the epidemic, and is cost-effective. Mass antigen testing is not cost-effective compared with mass nucleic acid testing in the same screening frequency. It would be more cost-effective to use AT as a supplemental screening tool when NAT capacity is insufficient or when outbreaks are spreading very rapidly.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1099116/fullCOVID-19cost-effectivenessscreening strategyagent-based modeldynamic zero-case policyChina |
| spellingShingle | Haonan Li Haonan Li Hui Zhang Hui Zhang Cost-effectiveness analysis of COVID-19 screening strategy under China's dynamic zero-case policy Frontiers in Public Health COVID-19 cost-effectiveness screening strategy agent-based model dynamic zero-case policy China |
| title | Cost-effectiveness analysis of COVID-19 screening strategy under China's dynamic zero-case policy |
| title_full | Cost-effectiveness analysis of COVID-19 screening strategy under China's dynamic zero-case policy |
| title_fullStr | Cost-effectiveness analysis of COVID-19 screening strategy under China's dynamic zero-case policy |
| title_full_unstemmed | Cost-effectiveness analysis of COVID-19 screening strategy under China's dynamic zero-case policy |
| title_short | Cost-effectiveness analysis of COVID-19 screening strategy under China's dynamic zero-case policy |
| title_sort | cost effectiveness analysis of covid 19 screening strategy under china s dynamic zero case policy |
| topic | COVID-19 cost-effectiveness screening strategy agent-based model dynamic zero-case policy China |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1099116/full |
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