Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases

Genipin is an important monoterpene iridoid compound isolated from <i>Gardenia jasminoides</i> J.Ellis fruits and from <i>Genipa americana</i> fruits, or genipap. It is a precursor of a blue pigment which may be attractive alternative to existing food dyes and it possesses va...

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Bibliographic Details
Main Authors: Magdalena Bryś, Karina Urbańska, Beata Olas
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/2/902
Description
Summary:Genipin is an important monoterpene iridoid compound isolated from <i>Gardenia jasminoides</i> J.Ellis fruits and from <i>Genipa americana</i> fruits, or genipap. It is a precursor of a blue pigment which may be attractive alternative to existing food dyes and it possesses various potential therapeutic properties such as anti-cancer, anti-diabetic and hepatoprotective activity. Biomedical studies also show that genipin may act as a neuroprotective drug. This review describes new aspects of the bioactivity of genipin against various diseases, as well as its toxicity and industrial applications, and presents its potential mechanism of action.
ISSN:1661-6596
1422-0067