Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases
Genipin is an important monoterpene iridoid compound isolated from <i>Gardenia jasminoides</i> J.Ellis fruits and from <i>Genipa americana</i> fruits, or genipap. It is a precursor of a blue pigment which may be attractive alternative to existing food dyes and it possesses va...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/2/902 |
| _version_ | 1797493273446580224 |
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| author | Magdalena Bryś Karina Urbańska Beata Olas |
| author_facet | Magdalena Bryś Karina Urbańska Beata Olas |
| author_sort | Magdalena Bryś |
| collection | DOAJ |
| description | Genipin is an important monoterpene iridoid compound isolated from <i>Gardenia jasminoides</i> J.Ellis fruits and from <i>Genipa americana</i> fruits, or genipap. It is a precursor of a blue pigment which may be attractive alternative to existing food dyes and it possesses various potential therapeutic properties such as anti-cancer, anti-diabetic and hepatoprotective activity. Biomedical studies also show that genipin may act as a neuroprotective drug. This review describes new aspects of the bioactivity of genipin against various diseases, as well as its toxicity and industrial applications, and presents its potential mechanism of action. |
| first_indexed | 2024-03-10T01:17:39Z |
| format | Article |
| id | doaj.art-fee61d6ab2fc457885b286c6d2bd7372 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T01:17:39Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-fee61d6ab2fc457885b286c6d2bd73722023-11-23T14:06:23ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-01-0123290210.3390/ijms23020902Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human DiseasesMagdalena Bryś0Karina Urbańska1Beata Olas2Department of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/3, 90-236 Lodz, PolandFaculty of Medicine, Medical University of Lodz, 90-419 Lodz, PolandDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/3, 90-236 Lodz, PolandGenipin is an important monoterpene iridoid compound isolated from <i>Gardenia jasminoides</i> J.Ellis fruits and from <i>Genipa americana</i> fruits, or genipap. It is a precursor of a blue pigment which may be attractive alternative to existing food dyes and it possesses various potential therapeutic properties such as anti-cancer, anti-diabetic and hepatoprotective activity. Biomedical studies also show that genipin may act as a neuroprotective drug. This review describes new aspects of the bioactivity of genipin against various diseases, as well as its toxicity and industrial applications, and presents its potential mechanism of action.https://www.mdpi.com/1422-0067/23/2/902genipinblue colorantbiological activitysafety |
| spellingShingle | Magdalena Bryś Karina Urbańska Beata Olas Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases International Journal of Molecular Sciences genipin blue colorant biological activity safety |
| title | Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases |
| title_full | Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases |
| title_fullStr | Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases |
| title_full_unstemmed | Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases |
| title_short | Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases |
| title_sort | novel findings regarding the bioactivity of the natural blue pigment genipin in human diseases |
| topic | genipin blue colorant biological activity safety |
| url | https://www.mdpi.com/1422-0067/23/2/902 |
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