Assessment of the effectiveness of two strategies of Antiretroviral therapy in Yemen
Objective: This study is aimed to compare two strategies of ART combination that are used for HIV-infected adult males in Yemen. Methods: This study was conducted in Al-Jumhori hospital-Sana’a-Yemen. Eighty six patients with positive HIV infection were treated with the first strategy and another for...
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| Format: | Article |
| Language: | English |
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University of Science and Technology, Yemen
2010-12-01
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| Series: | Yemeni Journal for Medical Sciences |
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| Online Access: | https://journals.ust.edu/index.php/yjms/article/view/252 |
| _version_ | 1828316068731420672 |
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| author | Doa’a A. Ibraheem Muna A. M. Elnemr |
| author_facet | Doa’a A. Ibraheem Muna A. M. Elnemr |
| author_sort | Doa’a A. Ibraheem |
| collection | DOAJ |
| description | Objective: This study is aimed to compare two strategies of ART combination that are used for HIV-infected adult males in Yemen. Methods: This study was conducted in Al-Jumhori hospital-Sana’a-Yemen. Eighty six patients with positive HIV infection were treated with the first strategy and another forty two patients age (22-65 years) were treated with the second strategy. Blood samples were collected and body weight was measured for the all patients before intake of ART combination and then after fifteen months and compared. Results: There was significant increase in the mean CD4 cell count in the second strategy (Lamivudine 150mg, Zidovudine 300mg and Nevirapine 200mg) from 173.4±15.20 to 250.2±25.0 (cells/mm3) (44.3%). Also there was significant increase in body weight from 54.29±1.08 to 56.72±1.13 kg (4.5%) compared with the first strategy (Lamivudine 150mg, Zidovudine 300mg and Nelfinavir 750mg orally) in which CD4 cell count from 238.7±21.9 to 328.95±21.6 (cells/mm3) (37.8%) and body weight from 54.38±1.69 to 55.99 kg (2.9%). Conclusion: The results demonstrate the activity of both strategies of ART combination in Yemen through reducing termination of patients by death and improving the health status of patient through increasing body weight. |
| first_indexed | 2024-04-13T17:09:30Z |
| format | Article |
| id | doaj.art-fee62100acc04890a59003a68a442db7 |
| institution | Directory Open Access Journal |
| issn | 2227-9601 2227-961X |
| language | English |
| last_indexed | 2024-04-13T17:09:30Z |
| publishDate | 2010-12-01 |
| publisher | University of Science and Technology, Yemen |
| record_format | Article |
| series | Yemeni Journal for Medical Sciences |
| spelling | doaj.art-fee62100acc04890a59003a68a442db72022-12-22T02:38:21ZengUniversity of Science and Technology, YemenYemeni Journal for Medical Sciences2227-96012227-961X2010-12-0141182410.20428/YJMS.4.1.3216Assessment of the effectiveness of two strategies of Antiretroviral therapy in YemenDoa’a A. Ibraheem0Muna A. M. Elnemr1Assistant Professor of Pharmacology, Head of Pharmacology Department, Faculty of Medical Sciences, University of Science and TechnologyAssistant Professor of Pediatric, Faculty of Medical Sciences, University of Science and TechnologyObjective: This study is aimed to compare two strategies of ART combination that are used for HIV-infected adult males in Yemen. Methods: This study was conducted in Al-Jumhori hospital-Sana’a-Yemen. Eighty six patients with positive HIV infection were treated with the first strategy and another forty two patients age (22-65 years) were treated with the second strategy. Blood samples were collected and body weight was measured for the all patients before intake of ART combination and then after fifteen months and compared. Results: There was significant increase in the mean CD4 cell count in the second strategy (Lamivudine 150mg, Zidovudine 300mg and Nevirapine 200mg) from 173.4±15.20 to 250.2±25.0 (cells/mm3) (44.3%). Also there was significant increase in body weight from 54.29±1.08 to 56.72±1.13 kg (4.5%) compared with the first strategy (Lamivudine 150mg, Zidovudine 300mg and Nelfinavir 750mg orally) in which CD4 cell count from 238.7±21.9 to 328.95±21.6 (cells/mm3) (37.8%) and body weight from 54.38±1.69 to 55.99 kg (2.9%). Conclusion: The results demonstrate the activity of both strategies of ART combination in Yemen through reducing termination of patients by death and improving the health status of patient through increasing body weight.https://journals.ust.edu/index.php/yjms/article/view/252hiv- infected adult maleart combinationyemen |
| spellingShingle | Doa’a A. Ibraheem Muna A. M. Elnemr Assessment of the effectiveness of two strategies of Antiretroviral therapy in Yemen Yemeni Journal for Medical Sciences hiv- infected adult male art combination yemen |
| title | Assessment of the effectiveness of two strategies of Antiretroviral therapy in Yemen |
| title_full | Assessment of the effectiveness of two strategies of Antiretroviral therapy in Yemen |
| title_fullStr | Assessment of the effectiveness of two strategies of Antiretroviral therapy in Yemen |
| title_full_unstemmed | Assessment of the effectiveness of two strategies of Antiretroviral therapy in Yemen |
| title_short | Assessment of the effectiveness of two strategies of Antiretroviral therapy in Yemen |
| title_sort | assessment of the effectiveness of two strategies of antiretroviral therapy in yemen |
| topic | hiv- infected adult male art combination yemen |
| url | https://journals.ust.edu/index.php/yjms/article/view/252 |
| work_keys_str_mv | AT doaaaibraheem assessmentoftheeffectivenessoftwostrategiesofantiretroviraltherapyinyemen AT munaamelnemr assessmentoftheeffectivenessoftwostrategiesofantiretroviraltherapyinyemen |