Dietary patterns and the risk of Alzheimer’s disease in an elderly Iranian population: a case–control study
Abstract Background An increasing number of studies in Western countries have shown that healthy eating patterns have a protective effect against cognitive decline and dementia, however, information about this relationship among non-western populations with different cultural environments is scarce....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | Journal of Health, Population and Nutrition |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41043-023-00398-y |
| _version_ | 1797801413312512000 |
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| author | Rezvan Hashemi Zahra Vahabi Hamid Rasekhi Farideh Shiraseb Maryam Amini |
| author_facet | Rezvan Hashemi Zahra Vahabi Hamid Rasekhi Farideh Shiraseb Maryam Amini |
| author_sort | Rezvan Hashemi |
| collection | DOAJ |
| description | Abstract Background An increasing number of studies in Western countries have shown that healthy eating patterns have a protective effect against cognitive decline and dementia, however, information about this relationship among non-western populations with different cultural environments is scarce. The present study investigated the association between dietary patterns (DPs) and cognitive function in the Iranian elderly. Methods In this case–control study, the data of 290 elderly people in two groups of case and control (Mean age in case: 74.2 ± 8.6, in control: 67.3 ± 7.3 year) were analyzed. Two DPs of healthy and unhealthy were extracted from a 142-item dish-based food frequency questionnaire, and patterns driven by principal components analysis (PCA) of 25 food groups. Multivariate binary logistic regression calculated the odds ratio (OR) of cognitive impairment with adjustment for potential confounding factors. Results A healthy DP, characterized by high consumption of fruits and vegetables, legumes, and nuts, was related to a decrease in the odds of Alzheimer’s disease in Iranian elderly people. Also, moderate adherence to an unhealthy food pattern was associated with an increase in the probability of the disease; however, the association was not statistically significant. Conclusion In this elderly population, a healthy eating pattern was associated with reducing the risk of Alzheimer’s disease. Further prospective studies are recommended. |
| first_indexed | 2024-03-13T04:50:05Z |
| format | Article |
| id | doaj.art-fee7320eae2b472ebc8bf48ec1b7c405 |
| institution | Directory Open Access Journal |
| issn | 2072-1315 |
| language | English |
| last_indexed | 2024-03-13T04:50:05Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Health, Population and Nutrition |
| spelling | doaj.art-fee7320eae2b472ebc8bf48ec1b7c4052023-06-18T11:17:24ZengBMCJournal of Health, Population and Nutrition2072-13152023-06-014211710.1186/s41043-023-00398-yDietary patterns and the risk of Alzheimer’s disease in an elderly Iranian population: a case–control studyRezvan Hashemi0Zahra Vahabi1Hamid Rasekhi2Farideh Shiraseb3Maryam Amini4Department of Geriatric Medicine, Ziaeian Hospital, Tehran University of Medical SciencesGeriatric Department, Tehran University of Medical SciencesDepartment of Nutrition Research, National Nutrition and Food Technology Research Institute and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical SciencesDepartment of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical SciencesDepartment of Nutrition Research, National Nutrition and Food Technology Research Institute and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical SciencesAbstract Background An increasing number of studies in Western countries have shown that healthy eating patterns have a protective effect against cognitive decline and dementia, however, information about this relationship among non-western populations with different cultural environments is scarce. The present study investigated the association between dietary patterns (DPs) and cognitive function in the Iranian elderly. Methods In this case–control study, the data of 290 elderly people in two groups of case and control (Mean age in case: 74.2 ± 8.6, in control: 67.3 ± 7.3 year) were analyzed. Two DPs of healthy and unhealthy were extracted from a 142-item dish-based food frequency questionnaire, and patterns driven by principal components analysis (PCA) of 25 food groups. Multivariate binary logistic regression calculated the odds ratio (OR) of cognitive impairment with adjustment for potential confounding factors. Results A healthy DP, characterized by high consumption of fruits and vegetables, legumes, and nuts, was related to a decrease in the odds of Alzheimer’s disease in Iranian elderly people. Also, moderate adherence to an unhealthy food pattern was associated with an increase in the probability of the disease; however, the association was not statistically significant. Conclusion In this elderly population, a healthy eating pattern was associated with reducing the risk of Alzheimer’s disease. Further prospective studies are recommended.https://doi.org/10.1186/s41043-023-00398-yAlzheimer’sFood patternsDementiaElderlyNutrition |
| spellingShingle | Rezvan Hashemi Zahra Vahabi Hamid Rasekhi Farideh Shiraseb Maryam Amini Dietary patterns and the risk of Alzheimer’s disease in an elderly Iranian population: a case–control study Journal of Health, Population and Nutrition Alzheimer’s Food patterns Dementia Elderly Nutrition |
| title | Dietary patterns and the risk of Alzheimer’s disease in an elderly Iranian population: a case–control study |
| title_full | Dietary patterns and the risk of Alzheimer’s disease in an elderly Iranian population: a case–control study |
| title_fullStr | Dietary patterns and the risk of Alzheimer’s disease in an elderly Iranian population: a case–control study |
| title_full_unstemmed | Dietary patterns and the risk of Alzheimer’s disease in an elderly Iranian population: a case–control study |
| title_short | Dietary patterns and the risk of Alzheimer’s disease in an elderly Iranian population: a case–control study |
| title_sort | dietary patterns and the risk of alzheimer s disease in an elderly iranian population a case control study |
| topic | Alzheimer’s Food patterns Dementia Elderly Nutrition |
| url | https://doi.org/10.1186/s41043-023-00398-y |
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