Leucine-rich Repeats and Immunoglobulin 1 (LRIG1) Ameliorates Liver Fibrosis and Hepatic Stellate Cell Activation via Inhibiting Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P) Pathway

Leucine-rich Repeats and Immunoglobulin 1 (LRIG1) Ameliorates Liver Fibrosis and Hepatic Stellate Cell Activation via Inhibiting Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P) Pathway

To detect the leucine-rich repeats and immunoglobulin 1 (LRIG1) ameliorated liver fibrosis and hepatic stellate cell (HSC) activation via inhibiting sphingosine kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P) pathway. C57BL/6 male mice (eight weeks old) were intraperitoneal injection with 10% carbon...

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Bibliographic Details
Main Authors: Wei Zhan, Xin Liao, Zhongsheng Chen, Lianghe Li, Tian Tian, Rui Li
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-08-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Carbon tetrachloride
Immunoglobulins
Leucine-rich repeats
Liver fibrosis
Sphingosine kinase
Sphingosine-1-phosphate
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2443

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